Treatment of thrombotic antiphospholipid syndrome: the rationale of current management—an insight into future approaches

CB Chighizola, T Ubiali… - Journal of Immunology …, 2015 - Wiley Online Library
thrombosis and pregnancy morbidity represent the clinical manifestations of antiphospholipid
syndrome … characterized by the persistent positivity of antiphospholipid antibodies (aPL). …

Thrombotic antiphospholipid syndrome: a practical guide to diagnosis and management

Z Sayar, R Moll, D Isenberg, H Cohen - Thrombosis research, 2021 - Elsevier
… vessel thrombosis is best described in the context of catastrophic antiphospholipid syndrome
… Small vessel thrombosis also occurs in the subacute/chronic setting, although the literature …

Management of thrombotic antiphospholipid syndrome

CB Chighizola, MG Raimondo… - Seminars in thrombosis …, 2018 - thieme-connect.com
… positivity for antiphospholipid antibodies (aPL) is required to diagnose antiphospholipid
syndrome (APS), an autoimmune disease characterized by recurrent vascular thrombosis and/or …

Antiphospholipid syndrome

G Ruiz-Irastorza, M Crowther, W Branch… - The Lancet, 2010 - thelancet.com
… Research shows the central role of endothelial cells, monocytes, platelets, and complement
in induction of thrombosis and fetal death in antiphospholipid syndrome. Endothelial cells …

Antiphospholipid syndrome

LR Sammaritano - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
… antibody profile and on the presence of additional thrombotic risk factors. Current standard
treatment for unprovoked thrombosis is long-term warfarin or other vitamin K antagonist …

Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
… APS can present with a variety of clinical phenotypes, including thrombosis in … thrombosis,
but other factors such as complement activation might be important. Prevention of thrombotic

[HTML][HTML] Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised …

H Cohen, BJ Hunt, M Efthymiou… - The Lancet …, 2016 - thelancet.com
… RAPS is slightly larger than the two previous randomised controlled trials in patient with
thrombotic antiphospholipid syndrome, and our inclusion criteria enabled recruitment of a more …

The antiphospholipid syndrome

JS Levine, DW Branch, J Rauch - New England Journal of …, 2002 - Mass Medical Soc
… Finally, thrombosis in the antiphospholipid syndrome has been likened to that in heparin-induced
thrombocytopenia. Both syndromes induce thrombosis … , the site of thrombosis is often …

The antiphospholipid syndrome

JH Rand - Annual review of medicine, 2003 - annualreviews.org
The antiphospholipid (aPL) antibody syndrome is an autoimmune condition in which vascular
thrombosis and/or recurrent pregnancy losses occur in patients with laboratory evidence …

Antiphospholipid syndrome

M Khamashta, M Taraborelli, S Sciascia… - Best practice & research …, 2016 - Elsevier
Antiphospholipid syndrome (APS) is an autoimmune condition characterized by the
occurrence of thrombosis (arterial and/or venous), often multiple, and/or morbidity in pregnancy (…