… transporter-1 (ENT1) messenger ribonucleic acid (mRNA) expression (R=0.03; P=0.90). (b)
There was a correlation between FLT SUV and thymidine kinase-1 (TK1) mRNA expression, …

… F-FLT) PET and the expression of the proliferation marker Ki-67, and the protein expression
and enzymatic activity of thymidine kinase-1 (… ) of 18 F-FLT PET images were performed in a …

… The present study investigated the relationship between the kinetic parameters of 18 F-FLT
in vivo and thymidine kinase-1 (TK-1) expression and cell proliferation rate in vitro, and blood…

… (FLT) is a good substrate for cytosolic thymidine kinase (TK-1)… FLT, FMAU is a better substrate
for mitochondrial thymidine … ENT1 expression might not reflect accumulation of FLT in vivo …

… FLT is accepted as a substrate by thymidine kinase 1 (TK-1), which phosphorylates it, thereby
trapping it in cells.44, 58, 59 FLT… , 83 In terms of radiation exposure, 18 F-FLT administered …

… FLT is phosphorylated by thymidine kinase 1 (TK 1 ) but not … in TK 1 protein levels, FLT
uptake, PCNA expression and ATP … The uptake of 3′-deoxy-3′-[18F]fluorothymidine into …

… F-FLT is taken up by both passive diffusion and facilitated transport by Na + -dependent
carriers and is then phosphorylated by thymidine kinase 1 (TK 1 ) to 18 F-FLT-… (18F)FLT PET for …

… by thymidine kinase 1 (TK1), at which point it becomes trapped in the cells. As a pyrimidine
analog, FLT … Using TaqMan analysis, we determined the baseline mRNA expression of 7 …

… specificity of TK1 expression and the extent to which tumors utilize thymidine salvage for …
FLT is monophosphorylated in a reaction catalyzed by the cytosolic enzyme thymidine kinase 1 …

… between endogenous thymidine concentrations and [18F]FLT uptake in a … F]FLT is
phosphorylated, and consequently trapped in cells, by thymidine kinase 1 (TK1), whose expression …