Correlation of 18F-FLT uptake with equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in gastrointestinal cancer
R Kameyama, Y Yamamoto, K Izuishi… - Nuclear medicine …, 2011 - journals.lww.com
… by nucleoside transporters, probably mainly by the equilibrative nucleoside transporter-1
(… within the cytosol after being monophosphorylated by thymidine kinase-1 (TK1), a principal …
(… within the cytosol after being monophosphorylated by thymidine kinase-1 (TK1), a principal …
The role of nucleoside/nucleotide transport and metabolism in the uptake and retention of 3′-fluoro-3′-deoxythymidine in human B-lymphoblast cells
DA Plotnik, LJ McLaughlin, J Chan… - Nuclear medicine and …, 2011 - Elsevier
… identified cell growth-dependent equilibrative nucleoside transporter-1 (hENT1) as a modifier
of … in thymidine kinase 1 (TK1) to study how metabolism and nucleoside transport influence …
of … in thymidine kinase 1 (TK1) to study how metabolism and nucleoside transport influence …
Correlation of 4′-[methyl-11C]-thiothymidine uptake with human equilibrative nucleoside transporter-1 and thymidine kinase-1 expressions in patients with newly …
Y Takami, Y Yamamoto, M Ueno, Y Chiba… - Annals of Nuclear …, 2018 - Springer
… nucleoside transporters, probably mainly by the human equilibrative nucleoside transporter-1
(… after being monophosphorylated by thymidine kinase-1 (TK1), one of the main enzyme in …
(… after being monophosphorylated by thymidine kinase-1 (TK1), one of the main enzyme in …
Effects of thymidylate synthase inhibition on thymidine kinase activity and nucleoside transporter expression
J Pressacco, B Mitrovski, C Erlichman, DW Hedley - Cancer research, 1995 - AACR
… Nucleoside transport appears to be an important step in the salvage of preformed nucleoside
… and specificity to NBMPR-sensitive nucleoside transport sites on the plasma membrane. …
… and specificity to NBMPR-sensitive nucleoside transport sites on the plasma membrane. …
[HTML][HTML] Crucial roles of thymidine kinase 1 and deoxyUTPase in incorporating the antineoplastic nucleosides trifluridine and 2'-deoxy-5-fluorouridine into DNA
K Sakamoto, T Yokogawa, H Ueno… - International …, 2015 - spandidos-publications.com
… as nucleoside transporters and dThd kinases (TK). TK1 is expressed in the cytoplasm during
S phase (8), while TK2 expression … 1) is a thymidine-derived nucleoside first synthesized by …
S phase (8), while TK2 expression … 1) is a thymidine-derived nucleoside first synthesized by …
Inhibition of nucleoside transport by protein kinase inhibitors
M Huang, Y Wang, SB Cogut, BS Mitchell… - Journal of Pharmacology …, 2003 - ASPET
… of the NBMPR-sensitive equilibrative transporter (ENT1). In this study … kinase inhibitors for
their effects on nucleoside transport. We find that incubation of K562 cells with tyrosine kinase …
their effects on nucleoside transport. We find that incubation of K562 cells with tyrosine kinase …
Physiological and pharmacological roles of nucleoside transporter proteins
M Molina-Arcas, L Trigueros-Motos… - Nucleosides …, 2008 - Taylor & Francis
… Moreover, transporter-mediated uptake of nucleoside-… data demonstrating that nucleoside
transporters, particularly CNTs, can … response triggered by nucleoside analogs in cancer cells. …
transporters, particularly CNTs, can … response triggered by nucleoside analogs in cancer cells. …
ABC transporters and their role in nucleoside and nucleotide drug resistance
Y Fukuda, JD Schuetz - Biochemical pharmacology, 2012 - Elsevier
… transport nucleoside drugs and nucleoside-monophosphate derivatives of clinically relevant
… Another ABC transporter implicated in nucleoside transport is the “half transporter,” ABCG2. …
… Another ABC transporter implicated in nucleoside transport is the “half transporter,” ABCG2. …
Mitochondrial expression of the human equilibrative nucleoside transporter 1 (hENT1) results in enhanced mitochondrial toxicity of antiviral drugs
Y Lai, CM Tse, JD Unadkat - Journal of Biological Chemistry, 2004 - ASBMB
… For example, the mitochondria-specific thymidine kinase (TK2) efficiently phosphorylates …
that one of these nucleoside transporters is the human equilibrative nucleoside transporter 1 (…
that one of these nucleoside transporters is the human equilibrative nucleoside transporter 1 (…
Nucleoside transport in normal and neoplastic cells
JA Belt, NM Marina, DA Phelps, CR Crawford - Advances in enzyme …, 1993 - Elsevier
… goals by examining the nucleoside transport properties of a … NUCLEOSIDE TRANSPORT
IN HUMAN CELL LINES Over the past few years we have examined the nucleoside transport …
IN HUMAN CELL LINES Over the past few years we have examined the nucleoside transport …
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