Human thymidine kinase 1. Regulation in normal and malignant cells
B Munch-Petersen, L Cloos, HK Jensen… - Advances in enzyme …, 1995 - Elsevier
… behavior of partly purified thymidine kinases from leukemic cells (59-62) … expression of
thymidine kinase activity in malignant cells (44, 47, 65). Deficient regulation of thymidine kinase …
thymidine kinase activity in malignant cells (44, 47, 65). Deficient regulation of thymidine kinase …
Thymidine kinase expression: a marker for malignant cells
M Hengstschläger, M Pfeilstöcker, E Wawra - Purine and pyrimidine …, 1998 - Springer
… expressed in malignant growing cells. Using a new cytofluorometric assay for thymidine kinase
in single cells… between normal growing cells and virally transformed cells or lines derived …
in single cells… between normal growing cells and virally transformed cells or lines derived …
Thymidine kinase, DNA synthesis and cancer
S Kit - Molecular and cellular biochemistry, 1976 - Springer
… The thymidine kinase isozymes of vertebrate cells have been characterized. Thymidine kinase
… when GI(Go) phase cells are stimulated or infected with oncogenic viruses. Chick cytosol …
… when GI(Go) phase cells are stimulated or infected with oncogenic viruses. Chick cytosol …
The role of thymidine kinase in cancer diseases
O Topolcan, L Holubec Jr - Expert opinion on medical diagnostics, 2008 - Taylor & Francis
… the S-phase of the cell cycle. In this review, the authors discuss serum levels of thymidine
kinase in a variety of neoplasias. Determination of thymidine kinase helps to monitor the follow-…
kinase in a variety of neoplasias. Determination of thymidine kinase helps to monitor the follow-…
Thymidine kinase and cancer monitoring
S Aufderklamm, T Todenhöfer, G Gakis, S Kruck… - Cancer letters, 2012 - Elsevier
… cell division. There is a feed-back regulation of the action of thymidine kinase in the cell:
thymidine … of the further phosphorylation of thymidine, acts as an inhibitor to thymidine kinase. …
thymidine … of the further phosphorylation of thymidine, acts as an inhibitor to thymidine kinase. …
[PDF][PDF] Thymidine kinase 1: a universal marker for cancer
MM Alegre, RA Robison, KL O'Neill - Cancer Clin Oncol, 2013 - pdfs.semanticscholar.org
… Although TK1 has been well-characterized as a serum biomarker and similar trends are
seen with tumor TK1, this study seeks to compare TK1 expression in a variety of solid tumors. In …
seen with tumor TK1, this study seeks to compare TK1 expression in a variety of solid tumors. In …
Thymidine kinase 1 through the ages: a comprehensive review
EE Bitter, MH Townsend, R Erickson, C Allen… - Cell & bioscience, 2020 - Springer
… They identified two isoenzymes of thymidine kinase that were termed fetal TK (TK1) and
adult TK (TK2) [33,34,35,36]. Originally, TK1 and TK2 were thought only to be expressed in fetal …
adult TK (TK2) [33,34,35,36]. Originally, TK1 and TK2 were thought only to be expressed in fetal …
Thymidine kinases: the enzymes and their clinical usefulness
BM Hannigan, YA Barnett, DBA Armstrong… - Cancer Biotherapy & …, 1993 - liebertpub.com
… viral enzymes, egthe HSV TK gene89, into tumor cells may render the tumor susceptible
to … ASSAYS OF THYMIDINE KINASE Thymidine kinase quantitation has conventionally …
to … ASSAYS OF THYMIDINE KINASE Thymidine kinase quantitation has conventionally …
Clinical value of thymidine kinase in patients with cervical carcinoma
R Fujiwaki, K Hata, M Moriyama, O Iwanari… - Oncology, 2001 - karger.com
… to determine the clinical value of thymidine kinase (TK), which … Methods: We examined
TK mRNA expression by reverse … synthase (TS) and thymidine phosphorylase (TP) mRNA …
TK mRNA expression by reverse … synthase (TS) and thymidine phosphorylase (TP) mRNA …
Thymidine kinase: diagnostic and prognostic potential
KL O'Neill, MR Buckwalter… - Expert review of molecular …, 2001 - Taylor & Francis
… A new monoclonal antibody assay for thymidine kinase has been developed, which is
capable of detecting thymidine kinase in both serum and tumor tissue. Thymidine kinase assay …
capable of detecting thymidine kinase in both serum and tumor tissue. Thymidine kinase assay …
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