… behavior of partly purified thymidine kinases from leukemic cells (59-62) … expression of
thymidine kinase activity in malignant cells (44, 47, 65). Deficient regulation of thymidine kinase …

… expressed in malignant growing cells. Using a new cytofluorometric assay for thymidine kinase
in single cells… between normal growing cells and virally transformed cells or lines derived …

… The thymidine kinase isozymes of vertebrate cells have been characterized. Thymidine kinase
… when GI(Go) phase cells are stimulated or infected with oncogenic viruses. Chick cytosol …

… the S-phase of the cell cycle. In this review, the authors discuss serum levels of thymidine
kinase in a variety of neoplasias. Determination of thymidine kinase helps to monitor the follow-…

… cell division. There is a feed-back regulation of the action of thymidine kinase in the cell:
thymidine … of the further phosphorylation of thymidine, acts as an inhibitor to thymidine kinase. …

… Although TK1 has been well-characterized as a serum biomarker and similar trends are
seen with tumor TK1, this study seeks to compare TK1 expression in a variety of solid tumors. In …

… They identified two isoenzymes of thymidine kinase that were termed fetal TK (TK1) and
adult TK (TK2) [33,34,35,36]. Originally, TK1 and TK2 were thought only to be expressed in fetal …

… viral enzymes, egthe HSV TK gene89, into tumor cells may render the tumor susceptible
to … ASSAYS OF THYMIDINE KINASE Thymidine kinase quantitation has conventionally …

… to determine the clinical value of thymidine kinase (TK), which … Methods: We examined
TK mRNA expression by reverse … synthase (TS) and thymidine phosphorylase (TP) mRNA …

… A new monoclonal antibody assay for thymidine kinase has been developed, which is
capable of detecting thymidine kinase in both serum and tumor tissue. Thymidine kinase assay …