… transporter-1 (hENT1) as a modifier of 3′-fluoro-3′-deoxythymidine (FLT) uptake … in
thymidine kinase 1 (TK1) to study how metabolism and nucleoside transport influence FLT uptake …

… and nucleoside transport rates of the six nucleosides tested … In summary, these nucleosides
are unpredictably cytotoxic to … expression characteristic; their uptake by cells engineered to …

… uptake of exogenous nucleosides is suggested by its evolutionary conservation. Furthermore,
the selective uptake … of a nucleotidebinding domain in HSV-1 thymidine kinase: effects on …

… that ENT1 activity and FLT uptake were not related. … nucleoside transporter-1 (ENT1) [ 4–6
]. This tracer is trapped within the cytosol after being monophosphorylated by thymidine kinase…

… from the extracellular fluid and phosphorylation by thymidine kinase in the salvage pathway.
… to increase nucleoside analogue uptake, this has been attributed to effects in kinases(31). …

… examine a mutant lacking thymidine kinase. There may be other nucleoside-specific proteins
… Finally, since our measurements of uptake and accumulation of thymidine are dependent …

… thymidine (Thd) kinase (TK) of herpes simplex virus type 1 (HSV-1) on the intracellular uptake
and anabolism of nucleosides … The cellular uptake of thymidine was highly dependent on …

… Thymidine uptake and incorporation and thymidine kinase … of thymidine incorporation
demonstrated thymidine uptake as … of thymidine kinase and a nonspecific nucleoside kinase which …

… The cellular uptake of thymidine and its phosphorylation are … thymidine analogues reflects
the activity of thymidine kinase (… /tk+ cells offering our fluorescent nucleosides as substrate. In …

… nucleoside or nucleoside analog to initiate uptake. At appropriate times, 160-μl aliquots
of cell suspension were withdrawn, and cells were separated by centrifugation through a …