Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth
C Carnrot, R Wehelie, S Eriksson… - Molecular …, 2003 - Wiley Online Library
… uptake … uptake experiment was distributed as nucleoside, nucleotides and nucleic acids;
∼ 9% was detected as dThd, ∼ 68% as thymidine monophosphate (dTMP), ∼ 1% as thymidine …
∼ 9% was detected as dThd, ∼ 68% as thymidine monophosphate (dTMP), ∼ 1% as thymidine …
Induction of thymidine kinase 1 after 5-fluorouracil as a mechanism for 3′-deoxy-3′-[18F] fluorothymidine flare
… thymidine kinase 1 (TK1) activity and nucleoside transporter expression to regulate intracellular
thymidine … The standardized uptake value (SUV) of each tumor was calculated from the …
thymidine … The standardized uptake value (SUV) of each tumor was calculated from the …
Kinetics of thymidine uptake, its phosphorylation, and incorporation into DNA in the sugar-beet cell culture
AV Nosov, IN Smolenskaya - Russian journal of plant physiology, 2002 - Springer
… thymidine kinase was isolated and, to some extent, purified. This gap was filled with our
studies on isolation and characterization of thymidine kinase … nucleosides on thymidine uptake, …
studies on isolation and characterization of thymidine kinase … nucleosides on thymidine uptake, …
Synthesis and Evaluation of [18F] Labeled Pyrimidine Nucleosides for Positron Emission Tomography Imaging of Herpes Simplex Virus 1 Thymidine Kinase Gene …
N Pillarsetty, S Cai, L Ageyeva, RD Finn… - Journal of medicinal …, 2006 - ACS Publications
… uptake in wild-type RG2 cells. Thus, background activity due to phosphorylation by endogenous
mammalian thymidine kinase in … to higher specificity for HSV1 thymidine kinase activity. …
mammalian thymidine kinase in … to higher specificity for HSV1 thymidine kinase activity. …
SPECT Imaging of Herpes Simplex Virus Type1 Thymidine Kinase Gene Expression By [123I] FIAU1
SR Choi, ZP Zhuang, AM Chacko, PD Acton… - Academic radiology, 2005 - Elsevier
… enzymes for the de novo synthesis of nucleosides. Thymidine kinase (TK) is a key enzyme
… At 5, 15, 30, 60, and 120 minutes, the cellular uptake of the nucleoside clearly demonstrated …
… At 5, 15, 30, 60, and 120 minutes, the cellular uptake of the nucleoside clearly demonstrated …
Validation of FLT uptake as a measure of thymidine kinase-1 activity in A549 carcinoma cells
JS Rasey, JR Grierson, LW Wiens… - Journal of Nuclear …, 2002 - Soc Nuclear Med
… FLT uptake predicted the activity of cytosolic thymidine kinase-1 (TK … Uptake of radiolabeled
FLT was compared with cell cycle … in the nucleoside salvage pathway to convert thymidine to …
FLT was compared with cell cycle … in the nucleoside salvage pathway to convert thymidine to …
Thymidine kinase, DNA synthesis and cancer
S Kit - Molecular and cellular biochemistry, 1976 - Springer
… in nucleotide synthesis. Especially striking is the increase of thymidine kinase activity, …
Some serum factors, such as insulin, act at the cell surface and increase the uptake of low …
Some serum factors, such as insulin, act at the cell surface and increase the uptake of low …
Mitochondrial thymidine kinase inhibitors
MJ Pérez-Pérez, AI Hernández… - Current Topics in …, 2005 - ingentaconnect.com
… Both thymidine kinases show important differences in their … it is virtually the only thymidine
kinase that is physiologically active … thymidine kinase gene: molecular cloning and nucleotide …
kinase that is physiologically active … thymidine kinase gene: molecular cloning and nucleotide …
Upregulation of thymidine kinase activity compensates for loss of thymidylate synthase activity in Mycoplasma pneumoniae
L Wang, C Hames, SR Schmidl… - Molecular …, 2010 - Wiley Online Library
… 0.57%, while the level of uptake in wild-type cells was at … 5% of total uptake was found in the
soluble nucleosides and … , 10% of total uptake was incorporated into soluble nucleoside and …
soluble nucleosides and … , 10% of total uptake was incorporated into soluble nucleoside and …
Radiolabelled pyrimidine nucleosides to monitor the expression of HSV-1 thymidine kinase in gene therapy
LI Wiebe, EE Knaus, KW Morin - Nucleosides, Nucleotides & …, 1999 - Taylor & Francis
… Uptake of IVFRU and FIRU in non-transduced KBALB cells was negligible in vitro, but uptake
of FIAU … Low uptake of radioactivity by non-target tissues, and favorable tumor: blood ratios …
of FIAU … Low uptake of radioactivity by non-target tissues, and favorable tumor: blood ratios …