… uptake … uptake experiment was distributed as nucleoside, nucleotides and nucleic acids;
∼ 9% was detected as dThd, ∼ 68% as thymidine monophosphate (dTMP), ∼ 1% as thymidine …

… thymidine kinase 1 (TK1) activity and nucleoside transporter expression to regulate intracellular
thymidine … The standardized uptake value (SUV) of each tumor was calculated from the …

… thymidine kinase was isolated and, to some extent, purified. This gap was filled with our
studies on isolation and characterization of thymidine kinase … nucleosides on thymidine uptake, …

… uptake in wild-type RG2 cells. Thus, background activity due to phosphorylation by endogenous
mammalian thymidine kinase in … to higher specificity for HSV1 thymidine kinase activity. …

… enzymes for the de novo synthesis of nucleosides. Thymidine kinase (TK) is a key enzyme
… At 5, 15, 30, 60, and 120 minutes, the cellular uptake of the nucleoside clearly demonstrated …

… FLT uptake predicted the activity of cytosolic thymidine kinase-1 (TK … Uptake of radiolabeled
FLT was compared with cell cycle … in the nucleoside salvage pathway to convert thymidine to …

… in nucleotide synthesis. Especially striking is the increase of thymidine kinase activity, …
Some serum factors, such as insulin, act at the cell surface and increase the uptake of low …

… Both thymidine kinases show important differences in their … it is virtually the only thymidine
kinase that is physiologically active … thymidine kinase gene: molecular cloning and nucleotide …

… 0.57%, while the level of uptake in wild-type cells was at … 5% of total uptake was found in the
soluble nucleosides and … , 10% of total uptake was incorporated into soluble nucleoside and …

… Uptake of IVFRU and FIRU in non-transduced KBALB cells was negligible in vitro, but uptake
of FIAU … Low uptake of radioactivity by non-target tissues, and favorable tumor: blood ratios …