… kinases. This mini-review attempts to summarize the biochemistry of the pyrimidine specific
thymidine kinase … the direct phosphorylation of deoxynucleosides imported from extracellular …

… Our results also confu-m the fact that dCK efficiently phosphorylates pyrimidine nucleosides
containing arabinosyl sugars while AraG appears to be a poor substrate for this enzyme. We …

… TK-2 resembles more the herpes simplex virus thymidine kinase (HSV-TK) than human
TK-1… activation of pyrimidine nucleosides and nucleoside analogues, thymidine kinases are an …

… The occurrence of two forms of cytosolic thymidine kinase with low and high catalytic activity…
the degree of activation of thymidine kinase targeted nucleoside analogs may depend on the …

… nucleosides to monophosphates and is expressed … thymidine kinase (TK1) and deoxycytidine
kinase (dCK), it has been difficult to determine the role of TK2 in activating nucleosides …

We describe the use of nonpolar nucleoside analogues of systematically varied size and …
thymidine kinases (TK1 and TK2) recognize and phosphorylate their substrate, thymidine. …

… The design concept for carboranyl pyrimidine nucleosides discussed in this paper explores
… elements between meta-carborane cluster and pyrimidine nucleoside scaffold, both at the 3-(…

… in the phosphorylation of pyrimidine nucleosides needed for mtDNA synthesis and could
also be involved in the mitochondrial toxicity associated to antiviral nucleoside analogues. …

… (dNK) that catalyzes the phosphorylation of pyrimidine … pathway to provide pyrimidine
nucleotides for mitochondrial DNA (… thymidine kinases in the activation of pyrimidine nucleoside …

… , whereas its ability to phosphorylate the purine nucleoside analogs ganciclovir (GCV)
and … of natural pyrimidine nucleosides (ie, thymidine) with purine nucleoside analogs for …