… Currently, only four drugs are approved for the treatment of DTC and MTC and several …
landscape and treatment of thyroid cancers, and the ongoing clinical and translational research …

… Thyroid cancer is an excellent model for studying tumor immune … The tumor immune
microenvironment of thyroid cancer is the heterogeneous histological space in which tumor cells …

… Since traditional cytotoxic systemic chemotherapy has had minimal efficacy in patients with
metastatic differentiated thyroid disease, ATA guidelines suggest starting treatment with a …

… Activating driver alterations in thyroid tumors leading to oncogene addiction are almost …
Clinical trials investigating tyrosine kinase inhibitors (TKIs) in advanced thyroid cancer over the …

… In order to better classify the molecular alterations detected in thyroid cancer, we will
initially discuss RTK-related upstream signaling pathways involved in tumorigenesis and …

… features and clinical behavior. The diagnostic definition, therapeutic approach, and follow-up
of thyroid cancers display some controversial aspects that represent unmet medical needs. …

… In thyroid cancer, based on preclinical and clinical data, we predict that there will be several
… therapeutic challenge in thyroid cancer patients, and identifying the mechanisms that allow …

… and firmly accelerate the clinical translation process of anti-thyroid cancer therapeutics. One
… development of a thyroid tumor, circumvent most problems associated with grafted models …

… thyroid cancer (MTC) presents several challenges. While MTC only accounts for <5% of
thyroid cancers (possibly even less with the incidental incidence of differentiated thyroid cancer …

… thyroid carcinomas and the identification of genomically targeted therapies to inhibit those
oncogenes have altered the treatment algorithm in thyroid cancer (… to describe challenges and …