… I ablation in only a minority of patients with thyroid cancer, a 2013 survey reported the use of
… of individualized therapies. In this Review, we discuss the personalized therapies for DTC …

… of thyroid cancer and, more importantly, could be related to their molecular profile (ie, genetic
and epigenetic alterations) (42, 48), likely because in differentiated thyroid cancers we do …

… More than that, some studies identified several genetic alterations as the vital determinant
or for the development of personalized therapies for thyroid cancer. By way of illustration, the …

… thyroid cancer (DTC) showed the need of a personalized management approach. Despite
the increased diagnosis of DTC, in particular small papillary thyroid cancers, cancer-… therapy …

… of thyroid cancer include B-Raf gene mutations, rearranged during transfection/ papillary
thyroid … overcome the lack of effective therapies for DTC, which are resistant to radioiodine and …

Thyroid cancer (TC) is the most prevalent endocrine malignancy. More than 90 % of TC is
represented by differentiated TC (DTC) arising from the follicular thyroid cells. DTC includes …

… Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer … of thyroid cancer, thus allowing more personalized treatments for patients with …

… The clinician and patient should discuss expectations regarding quality of life, and the
risks and benefits of therapy to determine the best personalized treatment plan. The treatment …

… more personalized approach to patients with follicular cell-derived thyroid cancer and point
… account for ~95% of cases and will be termed thyroid cancer for the purposes of this review. …

… Schematic of the two commonly activated pathways and genetic aberrations involved in
thyroid cancer, as well as the targeted therapies studied in thyroid cancer. The MAPK and the …