Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

M Xing, AS Alzahrani, KA Carson, D Viola, R Elisei… - Jama, 2013 - jamanetwork.com
… underestimate of the association of BRAF V600E with PTC mortality in … thyroid cancer in
conventionally high-risk patients, 3 which, as the present study showed, is where BRAF V600E

[PDF][PDF] BRAF (V600E) mutation and the biology of papillary thyroid cancer

F Frasca, C Nucera, G Pellegriti, P Gangemi… - … -related cancer, 2008 - academia.edu
BRAF(V600E) mutation is the most frequent genetic alteration in papillary thyroid carcinomas
(PTCs) that are 80–90% of all thyroid cancers. We evaluated the relationship between …

BRAFV600E Mutation is Associated with Tumor Aggressiveness in Papillary Thyroid Cancer

S Kim, KE Lee, JP Myong, J Park, YK Jeon… - World journal of …, 2012 - Springer
BRAF V600E mutation is the most common genetic alteration found in papillary thyroid cancer
(… the prevalence of the BRAF V600E mutation in tumor samples and its association with …

BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis

C Li, KC Lee, EB Schneider… - The Journal of Clinical …, 2012 - academic.oup.com
… presenting annually (seer.cancer.gov). The most common form of thyroid cancer is papillary
thyroid cancer (PTC), comprising 65–88% of all differentiated thyroid cancers (1). Although …

Correlation between the BRAF V600E Mutation and Tumor Invasiveness in Papillary Thyroid Carcinomas Smaller than 20 Millimeters: Analysis of 1060 Cases

F Basolo, L Torregrossa, R Giannini… - The Journal of …, 2010 - academic.oup.com
… The aim of the present study was to correlate BRAF V600E retrospectively with different clinical
… Moreover, we investigated the relationship between BRAF V600E and the degree of PTC …

[HTML][HTML] The BRAFV600E mutation: what is it really orchestrating in thyroid cancer?

C Nucera, J Lawler, R Hodin, S Parangi - Oncotarget, 2010 - ncbi.nlm.nih.gov
… aggressiveness will help establish a novel paradigm for treatment of thyroid cancers harboring
BRAF V600E . Furthermore, identifying downstream events from the BRAF V600E /ERK1/…

BRAFV600E and Microenvironment in Thyroid Cancer: A Functional Link to Drive Cancer Progression

C Nucera, J Lawler, S Parangi - Cancer research, 2011 - AACR
BRAF with knockdown, or using a drug (PLX4720) designed to selectively deactivate BRAF
V600E in those thyroid cancer … human thyroid cancer cells harboring BRAF V600E prevents …

Relationship between BRAF V600E and clinical features in papillary thyroid carcinoma

C Yan, M Huang, X Li, T Wang… - Endocrine connections, 2019 - ec.bioscientifica.com
… Between January 2015 and July 2018, 2850 patients were diagnosed with thyroid cancer. …
with other types of thyroid carcinoma. PTC patients without BRAF V600E status or lost to follow…

BRAFV600E Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer

S Fraser, C Go, A Aniss, S Sidhu, L Delbridge… - World journal of …, 2016 - Springer
… the impact of BRAF V600E in a large consecutive cohort of patients treated for thyroid cancer
at a single-tertiary Australian institution. The proportion of BRAF V600E -positive PTCs in …

Targeting BRAFV600E in thyroid carcinoma: therapeutic implications

CS Mitsiades, J Negri, C McMullan, DW McMillin… - Molecular cancer …, 2007 - AACR
… of BRAF V600E in thyroid carcinoma specimens and cell lines, we hypothesized that B-Raf
expression would be crucial in at least a subset of thyroid carcinomas. To deplete cells of …