[HTML][HTML] Thyroid carcinoma: molecular pathways and therapeutic targets

YE Nikiforov - Modern Pathology, 2008 - Elsevier
… follicular carcinomas, the second most common type of thyroid … the development of medullary
thyroid carcinomas. Many of … actively explored as therapeutic targets for thyroid cancer. A …

BRAF is a therapeutic target in aggressive thyroid carcinoma

G Salvatore, V De Falco, P Salerno, TC Nappi… - Clinical Cancer …, 2006 - AACR
… In papillary thyroid carcinomas, this mutation is associated with … BRAF as a potential therapeutic
target for thyroid carcinoma. … be an appealing therapeutic target for thyroid carcinomas, …

Thyrotropin suppressive therapy in thyroid carcinoma: what are the targets?

G Brabant - The Journal of Clinical Endocrinology & Metabolism, 2008 - academic.oup.com
Published guidelines on the treatment of thyroid carcinoma support TSH suppressive
therapy as the standard of care for long-term follow-up after initial surgery and sequential …

[HTML][HTML] Cancer stem cells as a potential therapeutic target in thyroid carcinoma

L Vicari, C Colarossi, D Giuffrida… - Oncology …, 2016 - spandidos-publications.com
… At present, the molecular pathogenesis of thyroid carcinomatherapies target mature
cancer cells and thus, thyroid CSCs, … therapeutic approaches that target thyroid CSCs (76–78). …

PI3K/Akt/mTOR: A promising therapeutic target for non-medullary thyroid carcinoma

MS Petrulea, TS Plantinga, JW Smit… - Cancer treatment …, 2015 - Elsevier
carcinoma (MTC). The follicular-derived TCs include several histological forms: papillary
thyroid carcinoma (PTC), follicular thyroid carcinoma (FTC… novel potential therapeutic targets for …

[HTML][HTML] Identification of potential therapeutic targets for papillary thyroid carcinoma by bioinformatics analysis

M Zhao, KJ Wang, Z Tan, CM Zheng… - Oncology …, 2016 - spandidos-publications.com
… study was to identify potential therapeutic targets for papillary thyroid carcinoma (PTC) and
… of normal thyroid tissues and 7 specimens of well‑differentiated thyroid carcinomas, were …

Targeted therapy: a new hope for thyroid carcinomas

F Perri, L Pezzullo, MG Chiofalo, S Lastoria… - Critical reviews in …, 2015 - Elsevier
… provided a list of possible molecular targets for biological therapy in thyroid carcinomas. …
a strong rationale for the use of targeted therapy for all histotypes of thyroid carcinomas. …

Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma: mutational and functional analysis

CS Mitsiades, V Kotoula, V Poulaki… - The Journal of …, 2006 - academic.oup.com
… chemotherapy (7), highlighting EGFR as a therapeutic target for any malignancies harboring
such mutations. All thyroid carcinoma cell lines in our panel were EGFR wild type and, in …

[PDF][PDF] Molecular genetics of medullary thyroid carcinoma: the quest for novel therapeutic targets

A Cerrato, V De Falco, M Santoro - Journal of molecular endocrinology, 2009 - Citeseer
Medullary thyroid carcinoma (MTC) is a rare tumour arising from neural crest-derived 2
parafollicular C cells. Metastatic MTC patients are incurable because the cancer does 3 not …

[HTML][HTML] Targeted molecular therapies in thyroid carcinoma

S Romagnoli, S Moretti, P Voce… - Arquivos Brasileiros de …, 2009 - SciELO Brasil
… , the majority are differentiated thyroid carcinomas (DTC), whose … Medullary thyroid carcinoma
has a worse prognosis, especially in … thyroid carcinomas showing very promising results. …