Immune profiling of thyroid carcinomas suggests the existence of two major phenotypes: an ATC-like and a PDTC-like

R Giannini, S Moretti, C Ugolini… - The Journal of …, 2019 - academic.oup.com
… The understanding of the mechanisms underlying thyroid cancer immune escape can lead to
immune expression profiling in thyroid cancers to obtain a comprehensive view on immune

Immune profiling of advanced thyroid cancers using fluorescent multiplex immunohistochemistry

J Ahn, M Jin, E Song, Y Ryu, DE Song, SY Kim, TY Kim… - Thyroid, 2021 - liebertpub.com
immune cell biomarkers can be evaluated using only two or three tissue sections if the multiplex
panel is applied to immune profiling… In conclusion, the immune profile obtained by using …

[HTML][HTML] Immune landscape of thyroid cancers: new insights

E Menicali, M Guzzetti, S Morelli, S Moretti… - Frontiers in …, 2021 - frontiersin.org
… classify thyroid tumors based on their immune signature. Finally, starting from the different
types of thyroid immune … (99) analyzed the immune expression profile in a collection of thyroid

[HTML][HTML] Immune profiling identifies CD8+ T-cell subset signatures as prognostic markers for recurrence in papillary thyroid cancer

Z Chen, ML Guo, YY Li, K Yan, L Li, F Shen… - Frontiers in …, 2022 - frontiersin.org
… To explore the immune microenvironment of thyroid, we collected thyroid tissues and … the
immune landscape of the thyroid and peripheral blood from MNG patients. Specific immune

Papillary thyroid carcinoma behavior: clues in the tumor microenvironment

K Bergdorf, DC Ferguson, M Mehrad… - Endocrine-Related …, 2019 - erc.bioscientifica.com
… of thyroid carcinoma is increasing and represents the most common endocrine malignancy,
with papillary thyroid carcinoma … We predict that the thyroid tumor immune microenvironment …

Immune profiling of medullary thyroid cancer—An opportunity for immunotherapy

K Hińcza-Nowak, A Kowalik, A Walczyk, I Pałyga… - Genes, 2021 - mdpi.com
immune cell populations; they also express immune checkpoint molecules that inhibit antitumor
immune … In this study, we used a panel to assess the expression profile of 395 genes in …

Immune cell confrontation in the papillary thyroid carcinoma microenvironment

Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
… , FPKM) of the thyroid carcinoma (THCA) dataset were downloaded from The Cancer Genome
Atlas (TCGA) (https://portal.gdc.cancer.gov/) and included 58 normal thyroid samples (N) …

The oncocytic variant of poorly differentiated thyroid carcinoma shows a specific immune-related gene expression profile

J Metovic, C Vignale, L Annaratone… - The Journal of …, 2020 - academic.oup.com
… A retrospective series of 48 PDTCs and 24 WDFCs was analyzed by means of NanoString
technology employing the nCounter PanCancer Immune Profiling panel. Gene expression …

Immune gene signature delineates a subclass of papillary thyroid cancer with unfavorable clinical outcomes

K Kim, S Jeon, TM Kim, CK Jung - Cancers, 2018 - mdpi.com
… In the present study, we obtained a large-scale gene expression profile of PTC including
tumor-adjacent normal thyroid tissue from TCGA consortium [6]. We applied NMF for …

The immune landscape of thyroid cancer in the context of immune checkpoint inhibition

G Varricchi, S Loffredo, G Marone, L Modestino… - International journal of …, 2019 - mdpi.com
… Combination strategies involving immune checkpoint inhibitors (ICIs) with tyrosine kinase (…
thyroid cancer. This review illustrates how different immune cells contribute to thyroid cancer …