… The newly discovered molecular features of well-differentiated thyroid carcinomas derived …
of thyroid tumours, under the following headings: “Follicular carcinoma”, “Papillary carcinoma”…

… This review summarises molecular pathological techniques applicable to thyroid FNA. The
molecular pathology of thyroid tumours is now fairly well understood. Molecular methods may …

… be a promising oncogene to target for personalized therapy in thyroid carcinomas (34).
Another oncogenic event in thyroid carcinomas has emerged. Mutations in the promoter region of …

… are associated to each thyroid tumor histotype: … the molecular biology of the differentiated
thyroid tumors, with particular interest in the associated genetic lesions and their role in thyroid …

… Thyroid cancer is the most common endocrine malignancy. Knowledge of the molecular
pathology of thyroid tumours … Common molecular alterations, such as BRAF p.V600E, RAS point …

… thyroid … carcinomas, and 3) BRAF and RAS molecular signatures have the potential of
subclassifying PTC and poorly differentiated thyroid carcinoma into clinically relevant molecular …

… and undifferentiated (anaplastic) thyroid carcinomas. Germline mutations of RET are
responsible for the development of heritable forms of medullary thyroid carcinoma (MTC) while …

… diagnostic, prognostic, and therapeutic relevance of the molecular features of thyroid tumors.
… molecular pathology that are (or may become) of practical interest to surgical pathologists. …

… risk of thyroid cancer of approximately 10%. Loss of PTEN activity also plays a role in …
thyroid carcinomas. Intragenic PTEN mutations are rare, particularly in well-differentiated thyroid …

… ongoing phase II trials of BAY 43-9006 (Sorafenib) in anaplastic thyroid carcinoma and
metastatic medullary thyroid carcinoma are yet to be released. It will be important to find whether …