… neoplasms has elucidated critical genetic pathways associated with the development of
specific thyroid tumor types. In papillary thyroid carcinoma (PTC), genetic events involve RET …

… In adults, the risk of developing thyroid carcinoma after … 1986, many children developed
papillary thyroid carcinoma after … -lived radioiodines were potent thyroid carcinogens in children, …

… Although we found a clearly increased risk for thyroid carcinoma patients to later develop
breast carcinoma, we were not able to address the etiology of the association conclusively. The …

… RET point mutations are crucial for the development of medullary thyroid carcinomas.
Many of these mutations, particularly those leading to the activation of the MAPK pathway, are …

… models which have a constitutively active Wnt/β-catenin pathway could help to understand
the mechanism by which the Wnt pathway promotes tumor development in thyroid cancer. …

… the thyroid gland of mice leads to the development of thyroid … transforming event during
thyroid tumor development (6). If … of the cancer cells in a given tumor should harbor this mutation. …

… The complex interactions between immune cells and tumor cells in cancer play a major
role in tumor development and subsequent patient outcomes. Different types of tumor-associated …

… , thyroid tumors in these transgenic mice show remarkable similarities to human … thyroid
carcinomas in many aspects. Based on our studies, it appears that thyroid tumor development …

… TRb1 and TRa1 in human papillary thyroid carcinomas (14). The … developed an advanced
lymphoma of unknown type at 10 months of age (results not shown). Carcinoma of the thyroid …

… thyroid concern the role ofprolonged elevation of circulating thyroid-stimulating hormone (TSH)
levels in the development of … circumstances, thyroid follicular cell tumors develop through …