Molecular testing for thyroid nodules: review and current state

MY Roth, RL Witt, DL Steward - Cancer, 2018 - Wiley Online Library
… initial therapy for suspected thyroid malignancies. This report briefly reviews the development
and current landscape of thyroid molecular testing in the management of thyroid nodules. …

Thyroid nodule molecular testing: is it ready for prime time?

TM Khan, MA Zeiger - Frontiers in Endocrinology, 2020 - frontiersin.org
… understanding of thyroid cancer biology, molecular testing needs to become more precise
and directed specifically toward informing what therapy to offer once thyroid cancer is …

Update on molecular testing for cytologically indeterminate thyroid nodules

M Nishino, M Nikiforova - Archives of pathology & …, 2018 - meridian.allenpress.com
molecular tests for thyroid cytology offer unique approaches to improve the risk stratification
of thyroid nodules… well as the emerging literature about test performance in the postvalidation …

Molecular testing for mutations in improving the fine-needle aspiration diagnosis of thyroid nodules

YE Nikiforov, DL Steward… - The Journal of …, 2009 - academic.oup.com
… Conclusions: These results indicate that molecular testing of thyroid nodules for a panel of
… value for thyroid nodules with indeterminate cytology. Palpable thyroid nodules are common …

Effectiveness of molecular testing techniques for diagnosis of indeterminate thyroid nodules: a randomized clinical trial

MJ Livhits, CY Zhu, EJ Kuo, DT Nguyen, J Kim… - JAMA …, 2021 - jamanetwork.com
… With a relatively high prevalence of malignancy of 28%, the DNA-RNA test had a … all nodules
with indeterminate cytology, while only 11% of nodules with benign molecular testing were …

The impact of molecular testing on the surgical management of patients with thyroid nodules

P Aragon Han, MT Olson, R Fazeli, JD Prescott… - Annals of surgical …, 2014 - Springer
… In this study, molecular testing of thyroid nodule did not alter the surgical management of
the majority of patients with thyroid nodules. These results indicate that molecular testing may …

Molecular testing for thyroid nodules including its interpretation and use in clinical practice

SG Patel, SE Carty, AJ Lee - Annals of surgical oncology, 2021 - Springer
… This overview describes the currently available molecular testing platforms and highlights
… validity and utility of molecular testing in the contemporary management of thyroid nodules. …

Molecular testing for thyroid nodules: the experience at McGill University teaching hospitals in Canada

M Rajab, RJ Payne, VI Forest, M Pusztaszeri - Cancers, 2022 - mdpi.com
… -up of the thyroid nodules can be considered [63]. To achieve this goal, a test with high …
with Bethesda III/IV thyroid nodules will benefit most from molecular testing at our center from a …

Molecular testing of thyroid nodules: a review of current available tests for fine-needle aspiration specimens

M Zhang, O Lin - Archives of pathology & laboratory …, 2016 - meridian.allenpress.com
… goal of thyroid molecular testing is to accurately assess the nature of thyroid nodules and
reduce the diagnostic uncertainty of cytologically indeterminate thyroid nodules before surgery. …

Centralized molecular testing for oncogenic gene mutations complements the local cytopathologic diagnosis of thyroid nodules

S Beaudenon-Huibregtse, EK Alexander, RB Guttler… - Thyroid, 2014 - liebertpub.com
… Background: Molecular testing for oncogenic gene mutations … of thyroid nodules, yet lacks
standardized testing modalities and … of molecular cytology on preoperative thyroid nodule fine-…