Conditional BRAFV600E Expression Induces DNA Synthesis, Apoptosis, Dedifferentiation, and Chromosomal Instability in Thyroid PCCL3 Cells
N Mitsutake, JA Knauf, S Mitsutake, C Mesa Jr, L Zhang… - Cancer research, 2005 - AACR
… following BRAF mutational activation in thyroid cells, we established doxycycline-inducible …
from rat thyroid PCCL3 cells. PCCL3 cells are well-differentiated thyroid cells that require …
from rat thyroid PCCL3 cells. PCCL3 cells are well-differentiated thyroid cells that require …
RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response
RET/PTC rearrangements represent key genetic events involved in papillary thyroid carcinoma
(PTC) initiation. The aim of the present study was to identify the early changes in gene …
(PTC) initiation. The aim of the present study was to identify the early changes in gene …
AMP-activated protein kinase upregulates glucose uptake in thyroid PCCL3 cells independent of thyrotropin
… PCCL3 cells To first analyze the involvement of AMPK in regulation of glucose uptake in thyroid
cells, we treated PCCL3 cells … Treatment of PCCL3 cells for 24 hours with AICAR elicited …
cells, we treated PCCL3 cells … Treatment of PCCL3 cells for 24 hours with AICAR elicited …
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway
HI Saavedra, JA Knauf, JM Shirokawa, J Wang… - Oncogene, 2000 - nature.com
… To explore this possibility we have modified the rat thyroid cell line PCCL3 to undergo …
involved in thyroid cell transformation. PCCL3 cells are derived from rat thyroid follicular cells and …
involved in thyroid cell transformation. PCCL3 cells are derived from rat thyroid follicular cells and …
Functional inactivation of thyroid transcription factor-1 in PCCl3 thyroid cells
C Christophe-Hobertus, A Lefort, F Libert… - Molecular and cellular …, 2012 - Elsevier
… thyroid-conditional hypomorphic mice concluded that this factor “may function to control the
proliferation of thyroid follicular cells … in the differentiated rat thyroid cell line PCCl3 a TTF-1 …
proliferation of thyroid follicular cells … in the differentiated rat thyroid cell line PCCl3 a TTF-1 …
[HTML][HTML] Differential gene expression analysis of iodide-treated rat thyroid follicular cell line PCCl3
… thyroid function remain unclear. In this paper, we analyze the transcriptome profile of the rat
follicular cell lineage PCCl3 … expression of essential genes for thyroid differentiation: Tshr, Nis…
follicular cell lineage PCCl3 … expression of essential genes for thyroid differentiation: Tshr, Nis…
Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3
S Rigutto, C Hoste, JE Dumont, B Corvilain… - Experimental Cell …, 2007 - Elsevier
… 2 O 2 in the rat thyroid cell line PCCl3. We showed that (1) Duox1 was abundantly expressed
in PCCl3 in regard to Duox2, contrary to what was observed in the rat thyroid tissue; (2) the …
in PCCl3 in regard to Duox2, contrary to what was observed in the rat thyroid tissue; (2) the …
Hormonal regulation of autophagy in thyroid PCCL3 cells and the thyroids of male mice
T Kurashige, Y Nakajima, M Shimamura… - Journal of the …, 2020 - academic.oup.com
… rat normal thyroid cell line PCCl3 to study the regulation of autophagy in vitro. The cells were
… , respectively, of autophagic activity, indicating that PCCl3 cells have functional autophagy. …
… , respectively, of autophagic activity, indicating that PCCl3 cells have functional autophagy. …
[HTML][HTML] Iodide treatment acutely increases pendrin (SLC26A4) mRNA expression in the rat thyroid and the PCCl3 thyroid cell line by transcriptional mechanisms
J Calil-Silveira, C Serrano-Nascimento… - Molecular and cellular …, 2012 - Elsevier
… mRNA expression in rat thyroid and in PCCl3 cells. Rats and cells were treated or not with
… SLC26A4 mRNA expression was also investigated in PCCl3 cells treated with actinomycin …
… SLC26A4 mRNA expression was also investigated in PCCl3 cells treated with actinomycin …
A validated LC-MS/MS method for cellular thyroid hormone metabolism: uptake and turnover of mono-iodinated thyroid hormone metabolites by PCCL3 thyrocytes
KH Richards, N Schanze, R Monk, E Rijntjes… - PLoS …, 2017 - journals.plos.org
… , in cell lysates of FBS-depleted rat thyroid epithelium PCCL3 cells. The methods for both …
pathways in cultured rat thyroid PCCL3 cells by incubating with 3-T 1 , 3-T 1 AM and 3-T 1 Ac. …
pathways in cultured rat thyroid PCCL3 cells by incubating with 3-T 1 , 3-T 1 AM and 3-T 1 Ac. …
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