Influence of stem cell therapy on thyroid function and reactive oxygen species production in diabetic rats

DLSG da Silva, ML de Freitas, GM Cahil… - Hormone and …, 2018 - thieme-connect.com
… of MSC treatment on thyroid H 2 O 2 generation in diabetic rats was due to a direct effect of
the mesenchymal stem cells, we co-cultured the rat thyroid cell line PCCL3, exposed or not to …

AMP-Activated Protein Kinase Activation Leads to Lysome-Mediated NA+/Iˉ-Symporter Protein Degradation in Rat Thyroid Cells

JM Cazarin, BM Andrade… - Hormone and metabolic …, 2014 - thieme-connect.com
… the lysosome pathway in thyroid cells. Rat follicular thyroid PCCL3 cells cultivated in Ham’s …
Treatment of PCCL3 cells with Bafilomycin A1 fully prevented the decrease of iodide uptake …

Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors

J Craps, C Wilvers, V Joris, B De Jongh… - …, 2015 - academic.oup.com
… HIF-1α protein expression in PCCL3 (G) and FRTL5 (H) cells and in human thyroid cells (I)
was analyzed by Western blotting. Blots on G and I originated from 2 different parts of the …

STAT3 negatively regulates thyroid tumorigenesis

JP Couto, L Daly, A Almeida, JA Knauf… - Proceedings of the …, 2012 - National Acad Sciences
… rat thyroid cell line, PCCl3, with either pCMV-BRAFV600E or pCMV expression vectors. The
addition of exogenous IL-6 on control (pCMV) transfected PCCl3 cells … -PCCl3 cells led to a …

The acute inhibitory effect of iodide excess on sodium/iodide symporter expression and activity involves the PI3K/Akt signaling pathway

C Serrano-Nascimento, S da Silva Teixeira… - …, 2014 - academic.oup.com
PCCl3 thyroid cells were cultured in Ham's F12 medium supplemented with 5% FBS, 1-mU/mL
bovine TSH, 10-μg/mL insulin, 5-μg/mL transferrin, and 10nM hydrocortisone at 37C in a …

[HTML][HTML] Investigating the mechanisms of action of thyroid disruptors: A multimodal approach that integrates in vitro and metabolomic analysis

NC Rolland, F Graslin, F Schorsch, T Pourcher… - Toxicology in Vitro, 2024 - Elsevier
… NIS activity was studied by measuring iodide uptake in PCCL3 cells. Rat follicular thyroid
PCCL3 cells were cultured in a 24-well plate with F12/Coon's 5% SVF medium (supplemented …

High‐level expression, activation, and subcellular localization of p38‐MAP kinase in thyroid neoplasms

M Pomerance, J Quillard, F Chantoux… - The Journal of …, 2006 - Wiley Online Library
… In this study, we have shown that p38α-MAPK is expressed in WRO and B-CPAP human
thyroid cell lines, in FRTL-5 and PCCL3 rat thyroid cell lines, and in pathological human …

Differential regulation of monocarboxylate transporter 8 expression in thyroid cancer and hyperthyroidism

J Badziong, S Ting, S Synoracki, V Tiedje… - European journal of …, 2017 - academic.oup.com
… in vitro experiments in rat thyroid PCCL3 cells and focused on MCT8… thyroid tissues and/or
malignant thyroid tumours. MCT8 expression and localization was determined in PCCL3 cells

[HTML][HTML] Association of Hashimoto's thyroiditis with thyroid cancer

G Azizi, JM Keller, M Lewis, K Piper… - Endocrine-related …, 2014 - erc.bioscientifica.com
… We demonstrated that in a rat thyroid cell line (PCCl3), non-… of DSBs in this cell line and
also in human thyroid in primary … was to compare, in a rat thyroid cell line (PCCl3) and in more …

Conditional activation of RET/PTC3 and BRAFV600E in thyroid cells is associated with gene expression profiles that predict a preferential role of BRAF in extracellular …

C Mesa Jr, M Mirza, N Mitsutake, M Sartor… - Cancer research, 2006 - AACR
… that PCCL3 thyroid cells conditionally … thyroid cells. To explore the early consequences
after activation of these oncoproteins, we did gene expression profiles of rat thyroid PCCL3 cells