TIM-3 as a prognostic marker and a potential immunotherapy target in human malignant tumors: a meta-analysis and bioinformatics validation
K Zang, L Hui, M Wang, Y Huang, X Zhu… - Frontiers in oncology, 2021 - frontiersin.org
… This study will provide more evidence to suggest whether TIM-3 could be a promising target
… In our study, the relationship between TIM-3 expression and prognosis was further validated …
… In our study, the relationship between TIM-3 expression and prognosis was further validated …
Integrated bioinformatic analysis and experimental validation for exploring the key immune checkpoint of COPD
J Ke, S Huang, Z He, S Lei, S Lin, M Duan - Gene, 2024 - Elsevier
… ) has been conducted, suggesting that Tim3 could be a promising … bioinformatics analysis
as being associated with CD8+ T cell immunity in COPD. We observed an upregulation of Tim3…
as being associated with CD8+ T cell immunity in COPD. We observed an upregulation of Tim3…
[HTML][HTML] Higher T cell immunoglobulin mucin-3 (Tim-3) expression in cervical cancer is associated with a satisfactory prognosis
Y Wang, S Zhao, X Zhang, H Zhu, X Ji… - Translational cancer …, 2020 - ncbi.nlm.nih.gov
… and experimental validation are needed in order to elucidate the exact role of Tim-3 in patients
with … exerts a detrimental effect on the progression of CC via bioinformatic screening. The …
with … exerts a detrimental effect on the progression of CC via bioinformatic screening. The …
TIM-3 dictates functional orientation of the immune infiltrate in ovarian cancer
J Fucikova, J Rakova, M Hensler, L Kasikova… - Clinical Cancer …, 2019 - AACR
… To validate these findings with another technique, we next analyzed the relationship between
PD-L1 expression and the intratumoral abundance of CD8 + CTLs by IHC (study group 1). …
PD-L1 expression and the intratumoral abundance of CD8 + CTLs by IHC (study group 1). …
In silico aptamer docking studies: from a retrospective validation to a prospective case study'tim3 aptamers binding
… In the previous validation, the 3D crystallographic structure of … TIM3 aptamers (our final
goal) is not at our disposal, the procedure to generate 3D RNA models was previously validated …
goal) is not at our disposal, the procedure to generate 3D RNA models was previously validated …
Molecular and clinical characterization of TIM-3 in glioma through 1,024 samples
… investigation of TIM-3 in glioma. Moreover, our findings were well validated in another RNA-…
genes respectively by GO analysis in DAVID Bioinformatics Resources 6.8. When the gene …
genes respectively by GO analysis in DAVID Bioinformatics Resources 6.8. When the gene …
Identification and validation of tumor stromal immunotype in patients with hepatocellular carcinoma
W Li, L Xu, J Han, K Yuan, H Wu - Frontiers in Oncology, 2019 - frontiersin.org
… In the present study, using CIBERSORT (a bioinformatics method), we estimated 22 types
of … TIM-3 and LAG3 expressions between two immune types were compared by continuous …
of … TIM-3 and LAG3 expressions between two immune types were compared by continuous …
Upregulation of Tim‐3 is associated with poor prognosis in acute myeloid leukemia
Z Wu, J Ou, N Liu, Z Wang, J Chen, Z Cai… - Cancer …, 2023 - Wiley Online Library
… that leukocyte Tim-3 was an independent prognostic factor for AML. To further validate this
… Additionally, this study confirmed the biology function of Tim-3 mainly by bioinformatics …
… Additionally, this study confirmed the biology function of Tim-3 mainly by bioinformatics …
Development and validation of a CD8+ T cell infiltration-related signature for melanoma patients
… and response to immunotherapy should be validated in a large and perspective study. …
We believe with the growing availability of high-dimensional database and bioinformatics …
We believe with the growing availability of high-dimensional database and bioinformatics …
Identification of an at-risk subpopulation with high immune infiltration based on the peroxisome pathway and TIM3 in colorectal cancer
J Yin, H Wang, Y Hong, A Ren, H Wang, L Liu, Q Zhao - BMC cancer, 2022 - Springer
… This study used two public patient datasets for discovery and validation. The CRC cohort …
3a and c). In addition, we adopted the same method to validate the existence of risk group III …
3a and c). In addition, we adopted the same method to validate the existence of risk group III …
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