Depth resolution and multiexponential lifetime analyses of reflectance-based time-domain fluorescence data

KM Tichauer, M Migueis, F Leblond, JT Elliott… - Applied Optics, 2011 - opg.optica.org
… in an inclusion could be measured based on differences in fluorescence lifetime while still
resolving the depth by fitting time-domain light diffusion models to reflectance FTPSFs. An …

Compressive hyperspectral time-resolved wide-field fluorescence lifetime imaging

Q Pian, R Yao, N Sinsuebphon, X Intes - Nature photonics, 2017 - nature.com
… of fluorescence lifetime-based biomarkers. As an intrinsic characteristic of a fluorophore and
its state, fluorescence lifetime … ) 10,11 with robustness because lifetime measurements are …

A time-resolved CMOS image sensor with draining-only modulation pixels for fluorescence lifetime imaging

Z Li, S Kawahito, K Yasutomi, K Kagawa… - … on Electron Devices, 2012 - ieeexplore.ieee.org
… Abstract—This paper presents a time-resolved CMOS image … , for timedomain fluorescence
lifetime imaging. In the DOM pixels using a pinned photodiode (PPD) technology, a time-…

Ultrafast confocal fluorescence microscopy beyond the fluorescence lifetime limit

H Mikami, J Harmon, H Kobayashi, S Hamad, Y Wang… - Optica, 2018 - opg.optica.org
… confocal fluorescence microscope that, for the first time to our knowledge, surpasses the
highest possible frame rate constrained only by the fluorescence lifetime … confocal fluorescence

48000 MHF: a dual-domain Fourier transform fluorescence lifetime spectrofluorometer

GW Mitchell, KM Swift - Time-Resolved Laser Spectroscopy in …, 1990 - spiedigitallibrary.org
… the time course of a sample's response to impulse excitation. Therefore, time domain
data is inherently available from the instrument and may be fitted to models of fluorescence

Time-resolved fluorescence microscopy

K Suhling, PMW French, D Phillips - Photochemical & Photobiological …, 2005 - pubs.rsc.org
… τ 0 = k r −1 is the natural or radiative lifetime which is related to the fluorescence lifetime τvia …
In the time domain, a fluorescence decay curve can be directly acquired after excitation of …

Fluorescence lifetime imaging by multi-dimensional time correlated single photon counting

W Becker - Medical Photonics, 2015 - Elsevier
… measure fluorescence lifetimes, and to combine fluorescence lifetime measurements with
imaging. The techniques can be classified into time-domain and frequency-domain techniques…

GPU acceleration of time-domain fluorescence lifetime imaging

G Wu, T Nowotny, Y Chen… - Journal of Biomedical …, 2016 - spiedigitallibrary.org
… a high-speed or even real-time FLIM system. FLIM can operate in the time domain or frequency
domain. Wide-field frequency-domain FLIM instruments are capable of capturing phase …

Quantitative FRET analysis by fast acquisition time domain FLIM at high spatial resolution in living cells

S Padilla-Parra, N Audugé, M Coppey-Moisan… - Biophysical journal, 2008 - cell.com
… Donor fluorescence lifetime decreases due to energy transfer in the excited … by fluorescence
lifetime measurements is advantageous in living cell studies since the fluorescence lifetime

Flow cytometric fluorescence lifetime measurements

HA Crissman, JA Steinkamp - Methods in Cell Biology, 2001 - Elsevier
fluorescence lifetimes: timedomain and frequency-domain analysis. In the time-domain method,
… light pulses, and the time evolution of the fluorescence emission is measured directly by …