… acidosis on myocardial contractility and energy production have been investigated in the
perfused rat heart. … B: Contribution of tissue acidosis to ischemic injury in the perfused rat heart. …

… & 12 (n = 8) in control and preconditioned hearts, respectively (P < 0.02). The … rat heart from
a prolonged period of ischemia. This protection is associated with decreased tissue acidosis …

… Sensitivity of myocardium to intracellular acidosis. This study demonstrates that aortic flow
in the working rat heart … of tissue acidosis to ischemic injury in perfused rat heart. Circulation …

… tissue pH with fast-responding extracellular electrodes shows that, in myocardial ischaemia,
tissue acidosis … and ischaemia on contractility and intracellular pH of rat heart. Circ Res 41: …

… that tissue acidosis, a result of an excess of hydrogen ion … fluorescence in hypoxia in the
working rat heart preparation … In conclusion, however, we suggest that tissue acidosis may …

… attributable to acidosis. More recently, myocardial tissue acidosis was proposed as a
primary cause of contractile failure during MI (2–4). In addition to myocardial acidosis related to …

… The isolated perfused working rat heart preparation has been used to study the effects of
respiratory acidosis on myocardial metabolism and contractilly. Hearts were perfused with 5 …

… tion of tissue acidosis to ischemic injury in the perfused rat heart. Circulation 53 (suppl I):
3-14 Zuurendonk PF, Tager JM (1974) Rapid separation of particulate components and soluble …

… metabolic acidosis (40). In addition, we investigate whether the reperfusioninduced changes
in tissue Na and HZ0 (14) are pH sensitive and whether the attenuating effect of acidosis on …

… the tissue acidosis that developed (in the blood-perfused tissue), suggesting that although
blood is a good buffer of tissue … that oligomycin treatment of isolated rat heart cells delayed the …