Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control

D Medrikova, ZM Jilkova, K Bardova… - … journal of obesity, 2012 - nature.com
… is associated with reduced adipose tissue macrophage infiltration and … tissue expandability
linked to adiponectin secretion might have a role in the sex differences observed in obesity

Adipose tissue expandability in the maintenance of metabolic homeostasis

SL Gray, AJ Vidal-Puig - Nutrition reviews, 2007 - academic.oup.com
… could be lost and regained at any time (FAT-ATTAC mouse). … Loss of adipose tissue from a
normal mouse results in a … tissue loss is induced in an obese mouse model (ob/ob mice), the …

Adipose tissue expandability: the metabolic problems of obesity may arise from the inability to become more obese

CY Tan, A Vidal-Puig - Biochemical Society Transactions, 2008 - portlandpress.com
… adipose tissue expandability and its implications in the management of … tissue expandability
hypothesis, these thinner mice had a more severe metabolic phenotype than the ob/ob mice

Adipose tissue expandability and the metabolic syndrome

M Slawik, AJ Vidal-Puig - Genes & nutrition, 2007 - Springer
… Similarly, PPARγ2 gene expression is increased in WAT by a high-fat diet (HFD) as well
as in mouse models of diet-induced obesity [11]. Studies using genetically modified mouse

Adipose tissue expandability, lipotoxicity and the metabolic syndrome—an allostatic perspective

S Virtue, A Vidal-Puig - Biochimica et Biophysica Acta (BBA)-molecular and …, 2010 - Elsevier
… expansion, both these models demonstrate a reduction in insulin sensitivity when compared
to the far more obese ob/ob mouse. Taken together the POKO and P465L DN × ob/ob …

Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4

O Gealekman, K Gurav, M Chouinard… - Journal of Biological …, 2014 - ASBMB
… on mouse adipose tissue sprouting and also suppressed sprouting from human subcutaneous
adipose tissue… , expanded adipose tissue, as decreased capillary density in obese human …

Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability

O Nov, H Shapiro, H Ovadia, T Tarnovscki, I Dvir… - PloS one, 2013 - journals.plos.org
… To gain further insight on the mechanisms for increased adipose tissue expandability in IL-1βKO-HFF
mice we assessed adipocyte size distribution. Using a semi-automated …

Adipose tissue function and expandability as determinants of lipotoxicity and the metabolic syndrome

S Carobbio, V Pellegrinelli, A Vidal-Puig - Obesity and lipotoxicity, 2017 - Springer
… (b) Adipose tissue expansion through hyperplasia and hypertrophy during the development
of obesity in diet-induced obese mice (HFD). The differences between depots are …

Angiogenesis in adipose tissue and obesity

S Corvera, J Solivan-Rivera, Z Yang Loureiro - Angiogenesis, 2022 - Springer
… Adipose tissue expandability is advantageous when … obesity and its many comorbidities.
The dense vasculature of adipose … in obese mice was found to be different from lean mice, and …

Molecular mechanism of obesity‐induced 'metabolic'tissue remodeling

M Tanaka, M Itoh, Y Ogawa… - Journal of diabetes …, 2018 - Wiley Online Library
… that macrophages infiltrate into obese adipose tissue in mice and humans14-16, … tissue
expandability during the development of obesity. Interestingly, Khan et al.33 reported that mice