… Thus, although fibrosis is most commonly referred to in its pathological context, the … of
tissue injury is also part of the normal physiological response to injury. An interrogation of “why” …

… fibrosis is most easily demonstrated by their role in collagen deposition. The net amount of
collagen accumulated after tissue injury … Fibrosis occurs when the synthesis of new collagen …

… tissue remodeling to reestablish normal function and integrity. However, their persistent
accumulation at the site of injury is a hallmark of fibrosis. … at the site of tissue injury and repair. …

… adaptive immune responses in regeneration, including both … players in the response to
tissue injury. Long recognized to … regeneration and fibrotic kidney repair in response to injury is …

… role in tissue repair and regeneration. Indeed, the immune response to tissue injury is crucial
in … repair, pro-fibrotic, anti-fibrotic, pro-resolving, and tissue regeneration characteristics are …

… ongoing tissue injury and to broadcast the news to cells suited at regenerating the tissue …
to ensure an effective healing of the tissue, yielding novel functional fibers. Conversely, they …

… a hamstring injury, in which the regeneration process could … presence of a fibrotic discontinuity
on muscle regeneration. In … regeneration of skeletal muscle in the presence of a fibrotic …

… Consistent with most soft-tissue injuries, immediate care for traumatic muscle injury focuses
on the RICE paradigm (rest, ice, compression, and elevation) to reduce blood flow and …

… of the liver, inflammation and necrosis of persistent hepatic tissues are usually described
as the cause of fibrosis and nodular regeneration (cirrhosis) which exceeds the capacity of …

… Induction and activation of TGF-β in tissue injury and fibrosis … in fibrotic tissues, regardless
of the etiology of the initial injury. … TGF-β isoform expression in fibrotic tissues. Neurohumoral …