The growing challenge of obesity and cancer: an inflammatory issue
AE Harvey, LM Lashinger… - Annals of the New York …, 2011 - Wiley Online Library
… of obesity, an established risk factor for many cancers, has risen … obesity–cancer link, with
particular emphasis on the impact of energy balance modulation, such as diet-induced obesity …
particular emphasis on the impact of energy balance modulation, such as diet-induced obesity …
Obesity programs macrophages to support cancer progression
… microenvironment in obesity, adipose tissue macrophages (… of macrophages in obesity-influenced
cancer progression. … and macrophage infiltration in the breast tissue of obese women. …
cancer progression. … and macrophage infiltration in the breast tissue of obese women. …
Obesity and cancer mechanisms: tumor microenvironment and inflammation
NM Iyengar, A Gucalp, AJ Dannenberg… - Journal of clinical …, 2016 - ascopubs.org
… obesity, which include cancer promotion. Our understanding of the mechanisms linking obesity
to cancer … Obesity is currently defined by an elevated body mass index (BMI), typically as …
to cancer … Obesity is currently defined by an elevated body mass index (BMI), typically as …
Role of adipose tissue macrophages in obesity-related disorders
… of the adipose tissue environment, while highlighting its heterogeneity. Finally, we detail
how obesity transforms both adipose tissue and local macrophage populations. Understanding …
how obesity transforms both adipose tissue and local macrophage populations. Understanding …
Insights into the link between obesity and cancer
SE Ackerman, OA Blackburn, F Marchildon… - Current obesity …, 2017 - Springer
… with metabolic dysfunction and poor cancer outcomes, suggesting … of adipose tissue caused
by obesity is linked to cancer. … that obesity drives activation of adipose tissue macrophages (…
by obesity is linked to cancer. … that obesity drives activation of adipose tissue macrophages (…
Obesity, inflammation, and cancer
… Activation of signal transducer and activator of transcription (STAT)6 by IL-4 drives expression
of an M2 macrophage phenotype in adipose tissue macrophages (ATMs) of lean mice that …
of an M2 macrophage phenotype in adipose tissue macrophages (ATMs) of lean mice that …
[HTML][HTML] Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg, D McCann, M Desai… - The Journal of …, 2003 - Am Soc Clin Investig
… adipose tissue demonstrates that adipose tissue macrophages … Adipose tissue macrophage
numbers increase in obesity and … that are activated in adipose tissues of obese individuals. …
numbers increase in obesity and … that are activated in adipose tissues of obese individuals. …
Metabolic regulation of adipose tissue macrophage function in obesity and diabetes
M Appari, KM Channon, E McNeill - Antioxidants & Redox Signaling, 2018 - liebertpub.com
… of macrophages in AT inflammation and obesity, and the metabolic changes in macrophage
… We highlight current targets for altering macrophage metabolism from both within the field of …
… We highlight current targets for altering macrophage metabolism from both within the field of …
Adipose tissue macrophages as potential targets for obesity and metabolic diseases
X Li, Y Ren, K Chang, W Wu, HR Griffiths, S Lu… - Frontiers in …, 2023 - frontiersin.org
… of macrophages and their roles in adipose tissue. While resident adipose tissue macrophages
… favorable beige adipose tissue, an increase in pro-inflammatory macrophages in adipose …
… favorable beige adipose tissue, an increase in pro-inflammatory macrophages in adipose …
Obesity and cancer: the role of dysfunctional adipose tissue
RCM Van Kruijsdijk, E Van Der Wall… - Cancer epidemiology …, 2009 - AACR
… between obesity and the occurrence of various cancers and to … adipose tissue dysfunction
has a prominent role in cancer … Adipose tissue macrophages are largely responsible for TNF-…
has a prominent role in cancer … Adipose tissue macrophages are largely responsible for TNF-…