[HTML][HTML] … and tumor cells recruit and modify macrophages to the mammary tumor microenvironment: the role of obesity and inflammation in breast adipose tissue

AM Santander, O Lopez-Ocejo, O Casas, T Agostini… - Cancers, 2015 - mdpi.com
… cells contributing to tumor macrophage recruitment. We hypothesize … in obese females and
plays a major role in breast cancer development. The effects of this interplay on macrophage

[HTML][HTML] Obesity induces a phenotypic switch in adipose tissue macrophage polarization

CN Lumeng, JL Bodzin, AR Saltiel - The Journal of clinical …, 2007 - Am Soc Clin Investig
… Adipose tissue macrophages (ATMs) infiltrate adipose tissue during obesity and contribute
to insulin resistance. We hypothesized that macrophages migrating to adipose tissue upon …

[HTML][HTML] Contribution of adipose tissue to development of cancer

AJ Cozzo, AM Fuller, L Makowski - Comprehensive Physiology, 2017 - ncbi.nlm.nih.gov
… ATM Adipose tissue macrophages … address epidemiologic links between obesity and cancer.
Subsequently, … links between cancer development or progression and adipose tissue per …

Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression

CA Gilbert, JM Slingerland - Annual review of medicine, 2013 - annualreviews.org
… The next sections of this review explore how cytokine production in adipocytes of obese
cancer patients may promote cancer cell invasion, metastasis, and CSC self-renewal. …

Adipose tissue macrophage phenotypes and characteristics: the key to insulin resistance in obesity and metabolic disorders

Y Ni, L Ni, F Zhuge, L Xu, Z Fu, T Ota - Obesity, 2020 - Wiley Online Library
… , were shown to be effective for obesity-induced IR and other … of macrophages in adipose
tissue under conditions of obesitymacrophages might be a key therapeutic target for obesity-…

Effects of obesity on the regulation of macrophage population in the prostate tumor microenvironment

GC Galvan, CB Johnson, RS Price, MA Liss… - … and cancer, 2017 - Taylor & Francis
… , we aimed to determine if obesity would promote more macrophage infiltration into the …
cancer cells themselves could also contribute to the production of CCL2, especially in an obese

Cancer as a matter of fat: the crosstalk between adipose tissue and tumors

E Lengyel, L Makowski, J DiGiovanni, MG Kolonin - Trends in cancer, 2018 - cell.com
… all female cancers currently diagnosed are obesity-associated, is particularly concerning. A
number of mechanisms have been proposed to explain the role of obesity in cancer risk and …

[HTML][HTML] Adipose tissue, obesity and adipokines: role in cancer promotion

A Booth, A Magnuson, J Fouts… - … molecular biology and …, 2015 - degruyter.com
… and women, the associated obesity risk with this cancer is greater in men than … obesity
increases the risk of colon cancer death in men only [7, 8]. In women, obesity-associated cancer

[HTML][HTML] Obesity and cancer: the oil that feeds the flame

J Font-Burgada, B Sun, M Karin - Cell metabolism, 2016 - cell.com
obesity epidemic had become a cocktail party cliché, its impact on public health cannot be
dismissed. In the past decade, cancer … understanding how obesity increases cancer risk and …

Local proliferation of macrophages in adipose tissue during obesity-induced inflammation

J Haase, U Weyer, K Immig, N Klöting, M Blüher… - Diabetologia, 2014 - Springer
Obesity is frequently associated with low-grade inflammation of adipose tissue (AT), and the
increase in adipose tissue macrophages … stroke, several types of cancer and type 2 diabetes …