… effects of obesity can occur at the … tissue inflammation, as well as paracrine and autocrine
effects. This Review explores key pathways linking visceral obesity and gastrointestinal cancer, …

… obese, with a BMI > 40 kg/m 2 (2). A recent summary by the International Agency for Research
on Cancer reinforced obesity as a risk factor of many cancer … or obese cancer patients, …

… In general, the inflammatory microenvironment polarizes tissue macrophages toward a …
in fatty liver disease–induced cancerous degeneration (most commonly, HCC) [11, 12]. …

… tissue macrophages (ATM) with astounding heterogeneity and complex regulation play a
decisive role in mediating obesity-… on the role of macrophages in the context of obesity-induced …

… and adipose tissues of obesity (5, 6). Moreover, it has been … that macrophages that accumulate
in tumor tissues or adipose tissues of obesity differentiate by interacting with cancer cells …

… The plasticity of macrophages in AT has recently been taken into account as the link between
obesity and cancer, where the polarization of macrophages in AT has been thought to be a …

… , dyslipidemia, accelerated atherosclerosis and even cancers. In recent years, it has also …
tissue macrophage (ATM) infiltration is crucial to the initiation of insulin resistance in the obese …

… infiltration in patients with modest obesity or early metabolic … of a macrophage phenotype
switch in visceral adipose tissue. … adipose tissue macrophages in patients with modest obesity …

… Obese adipose tissue macrophages express IL-17 and IL-22 receptor making them sensitive
to IL… 39; hence, the association between obesity and the significant increased risk of cancer. …

… Both compounds produced in the adipose tissue have an extraordinary … obesity and CRC
and the importance to consider obesity in the standard of care dealing with colorectal cancer …