… and activator of transcription 3 (STAT3) activity in epithelial, immune and stromal cells is
critical for wound healing and tissue repair. Excessive STAT3 activation within cancer cells and …

… The effects of STAT3 inhibition on cell fate and proliferation … pharmacological manipulation
of STAT3 activity can be used to … Administration of the Stat3 inhibitor accelerated tissue repair, …

… during physiologic tissue repair as well as in fibrotic diseases. However, while tissue remodeling
… g–j Relative luciferase activity in fibroblasts transfected with STAT3 luciferase reporter …

… Our findings provide evidence that antifibrotic STAT3 activities in myeloid cells are context-dependent
and vary regarding the nature of the tissue damage response. In a model of acute …

… Stat3 activity associated with wound healing in chronically inflamed mouse lungs and increased
Stat3 activity … Since Stat3 is upregulated by both tissue injury and oncogenic signals, our …

… While SOCS3 is the known regulator of STAT3 activity, SOCS1, which is known to … , STAT3
has the capacity to be activated by a broad spectrum of upstream tyrosine kinase activities …

… STAT3 has been shown to be activated in Pax7+ satellite cells after acute injury while satellite
cells engage in tissue repair [… demonstrate that normal STAT3 activity is required for proper …

… tissue trophic factor network can be activated by MSC-mediated JAK-STAT3 signaling for
tissue repair… Indeed, physical activity is known to prevent coronary artery disease and cognitive …

… of the STAT3 pathway mediated by IL-10, which results in HA regulation, may be a necessary
component for the recapitulation of true regenerative tissue repair, as shown in our studies. …

… Studies have shown that genders and sex steroids might affect tissue repair and … of cell
activity assays to test the effects of circ-Amotl1 on cell biology associated with wound repair. In …