… Summary: Rheumatoid arthritis is a chronic systemic … tissue reactivity in rheumatoid arthritis
with a focus on the dynamics controlling secondary and ectopic lymphoid tissue response. …

… As outlined earlier in this article, cytokines such as IL-1, IL-6 and TNF are key effectors of
the tissue response in RA. Stromal elements might act upstream of these cytokines (acting as …

… Rituximab is an effective treatment for rheumatoid arthritis (… depletion in the synovial tissue
of a subset of patients with RA3 … two studies on the synovial tissue response to rituximab in RA …

… In self-resolving inflammation (A) the immune response is generated by tissue signals (antigen…
The efficient removal of tissue signals blocks the generation of effector immune responses …

… Development and validation of response criteria in rheumatoid arthritis: steps towards an
international consensus on prognostic markers. Br J Rheumatol1996;35 (suppl 2) :4–7. …

… rheumatoid arthritis is complex involving both resident and infiltrating cells. The synovial
tissue … Some individuals proceed to develop a humoral immune response to these neo-epitopes …

… vasculature, are also present in the sublining layer, providing a link between the synovium
and systemic responses to changes within the tissue environment 16 . Across several …

… , the tissue responds with a maladaptive wound healing response, described as pannus
formation, which by itself has destructive features and will lead to irreversible tissue injury …

… tissue in patients with rheumatoid arthritis (RA) treated with rituximab and to identify possible
predictors of clinical response… The kinetics of the serological as well as the tissue response …

… Objective: The response of rheumatoid arthritis (RA) patients … synovial tissues from RA
patients and the clinical response to … Clinical response at 16 weeks was defined as a reduction in …