Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context
… underlying interindividual differences in tissue specific methylation that lead us to an
understanding of the nature of the relationships that govern these crucial tissue specific differences. …
understanding of the nature of the relationships that govern these crucial tissue specific differences. …
Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
… the tissue-specific DNA methylation patterns of rat against those of mouse and human …
three shared tissue types. We confirmed that tissue-specific differentially methylated regions …
three shared tissue types. We confirmed that tissue-specific differentially methylated regions …
Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer
… DNA methylation patterns of ten types of fetal tissue, in addition to matched normal-cancer
data for corresponding tissue … the level of aberrant cancer DNA methylation in gene promoters …
data for corresponding tissue … the level of aberrant cancer DNA methylation in gene promoters …
DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
… Our aim was to describe the general patterns of globally conserved and tissue-specific
DNA methylation with functional consequences in gene regulation. Using the high-density …
DNA methylation with functional consequences in gene regulation. Using the high-density …
Tissue-specific differences in DNA methylation in various mammals
MA Gama-Sosa, RM Midgett, VA Slagel… - … et Biophysica Acta (BBA …, 1983 - Elsevier
… of methylation of their cytosine residues. Several similarities in the patterns of tissue-specific
DNA methylation … Compared to most other types of DNA examined, brain and thymus DNAs …
DNA methylation … Compared to most other types of DNA examined, brain and thymus DNAs …
Tissue-specific DNA methylation profiles in newborns
E Herzog, J Galvez, A Roks, L Stolk, M Verbiest… - Clinical …, 2013 - Springer
… tissue-specific variation in DNA methylation of two imprinted genes in easily accessible
tissues… DNA methylation analysis of these genes in umbilical cord blood. The observed between-…
tissues… DNA methylation analysis of these genes in umbilical cord blood. The observed between-…
Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues
S Ghosh, AJ Yates, MC Frühwald, JC Miecznikowski… - Epigenetics, 2010 - Taylor & Francis
… human somatic tissues and fewer still have studied the same sets of tissues from multiple …
to study tissue specific methylation patterns in a set of twelve human tissues collected from …
to study tissue specific methylation patterns in a set of twelve human tissues collected from …
Development of tissue-specific age predictors using DNA methylation data
H Choi, S Joe, H Nam - Genes, 2019 - mdpi.com
… Thus, to address the tissue-specific characteristics of DNA methylation changes … , we
constructed tissue-specific chronological age predictors using DNA from the same tissues (Figure 1)…
constructed tissue-specific chronological age predictors using DNA from the same tissues (Figure 1)…
Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development
… DNA methylation has tissue specificity, that demethylation has a prominent role in tissue
differentiation, and that DNA methylation … changes in DNA methylation during development are …
differentiation, and that DNA methylation … changes in DNA methylation during development are …
Tissue‐specific dysregulation of DNA methylation in aging
… changes we observed are potentially valuable insights into the pathophysiology of aging, it
is the striking tissue specificity we observe that represents the most novel finding of our study. …
is the striking tissue specificity we observe that represents the most novel finding of our study. …
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