Efficacy of EGFR-TKI plus chemotherapy or monotherapy as first-line treatment for advanced EGFR-mutant lung adenocarcinoma patients with co-mutations

Z Yang, Y Chen, Y Wang, S Wang, M Hu… - Frontiers in …, 2021 - frontiersin.org
… -mutations can benefit from EGFR-TKIs plus chemotherapy. In our research, we collected
information on patients who used EGFR-TKIs plus chemotherapy and TKIs alone … co-mutations, …

Combination of EGFR-TKIs with chemotherapy versus chemotherapy or EGFR-TKIs alone in advanced NSCLC patients with EGFR mutation

M Wen, J Xia, Y Sun, X Wang, X Fu… - … : Targets and Therapy, 2018 - Taylor & Francis
… and EGFR-TKIs vs chemotherapy or EGFR-TKIs alone in … alone in the treatment of advanced
NSCLC. Otherwise, all the participants in this study had the positive EGFR mutation gene, …

[HTML][HTML] EGFR-TKI plus bevacizumab versus EGFR-TKI monotherapy for patients with EGFR mutation-positive advanced non-small cell lung cancer-A propensity …

JS Tsai, PL Su, SC Yang, CC Chang, CY Lin… - Journal of the Formosan …, 2021 - Elsevier
… patients with EGFR mutant NSCLC treated with EGFR-tyrosine kinase inhibitors (TKI) and
… Randomized phase III studies comparing other EGFR-TKIs alone or in combination with …

Combination of EGFR-TKIs and chemotherapy in advanced EGFR mutated NSCLC: Review of the literature and future perspectives

SE Rebuzzi, R Alfieri, S La Monica, R Minari… - Critical Reviews in …, 2020 - Elsevier
… plus chemotherapy reported promising efficacy and survival improvement compared to
EGFR-TKI and chemotherapy alone in EGFR-mutated NSCLC patients. They concluded that the …

[HTML][HTML] EGFR TKIs plus WBRT demonstrated no survival benefit other than that of TKIs alone in patients with NSCLC and EGFR mutation and brain metastases

T Jiang, C Su, X Li, C Zhao, F Zhou, S Ren… - Journal of Thoracic …, 2016 - Elsevier
… to EGFR TKIs resulted in even worse survival than TKIs alone in patients with BM and EGFR
mutations. … resulted in survival similar to that with chemotherapy alone in patients with BM. …

EGFR TKI combination with immunotherapy in non-small cell lung cancer

MJ Ahn, JM Sun, SH Lee, JS Ahn… - Expert opinion on drug …, 2017 - Taylor & Francis
… among EGFR-mutant patients was relatively low prior to EGFR TKIEGFR TKI alone. However,
only few immune checkpoint inhibitors have been studied as combination with EGFR TKIs

… -tyrosine kinase inhibitor (EGFR-TKI) alone or in combination with chemotherapy for advanced non-small cell lung cancer (NSCLC) with low-abundance mutation

X Yan, H Wang, P Li, G Zhang, M Zhang, J Yang… - Lung Cancer, 2019 - Elsevier
EGFR-TKI alone or in combination with chemotherapy in patients with low-abundance EGFR
mutations … effective treatment strategies for patients with low-abundance EGFR mutations. …

First-generation EGFR-TKI plus chemotherapy versus EGFR-TKI alone as first-line treatment in advanced NSCLC with EGFR activating mutation: a systematic review …

Q Wu, W Luo, W Li, T Wang, L Huang, F Xu - Frontiers in Oncology, 2021 - frontiersin.org
… Finally, eight studies comparing EGFR-TKI plus chemotherapy with EGFR-TKI alone as
first-line treatment in advanced non-small cell lung cancer with activating EGFR mutation were …

EGFR-TKIs plus chemotherapy demonstrated superior efficacy than EGFR-TKIs alone as first-line setting in advanced NSCLC patients with EGFR mutation and BIM …

S Liu, Y He, T Jiang, S Ren, F Zhou, C Zhao, X Li… - Lung Cancer, 2018 - Elsevier
… response to EGFR-tyrosine kinase inhibitors (TKIs). … of EGFR-TKIs plus chemotherapy
versus EGFR-TKIs alone as first-line treatment in advanced NSCLC patients with EGFR mutations

[HTML][HTML] EGFR-TKI plus brain radiotherapy versus EGFR-TKI alone in the management of EGFR-mutated NSCLC patients with brain metastases

K Dong, W Liang, S Zhao, M Guo, Q He… - Translational Lung …, 2019 - ncbi.nlm.nih.gov
… This study was mainly focused on the comparison of clinical efficacy between EGFR-TKIs
plus brain RT and EGFR-TKIs alone in EGFR mutant NSCLC patients with BM. And furtherly …