TNF-α in the cardiovascular system: from physiology to therapy

K Urschel, I Cicha - … Journal of Interferon, Cytokine and Mediator …, 2015 - Taylor & Francis
tumor necrosis factor alpha (TNF-α) play a key role in the cellular responses to inflammation
and injury. In the cardiovascular system, TNF-α-… , and adverse cardiac remodeling following …

Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease

M Azzawi, P Hasleton - Cardiovascular research, 1999 - academic.oup.com
… In this review, we consider the basic biology of TNFα in relation to certain cardiac diseases.
There are interrelationships between some of the conditions described, but these have been …

The characterization of tumor necrosis factor alpha (TNF-α), its role in cancerogenesis and cardiovascular system diseases and possibilities of using this cytokine as a …

B Grabarek, M Bednarczyk, U Mazurek - 2017 - dspace.uni.lodz.pl
… The studies and statistical data show how cancer and cardiovascular diseases are a
serious problem and highlight the need to find new diagnostic marker. TNFα can be used as a …

[HTML][HTML] The role of TNF-α in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk

C Popa, MG Netea, PLCM Van Riel… - Journal of lipid …, 2007 - ASBMB
… This review will focus on the role of TNF-α in the development of dyslipidemia … of cardiovascular
diseases and type 2 DM. Patients with RA have 1.5–2 times higher risk of cardiovascular

The influence of tumour necrosis factor-α on the cardiovascular system of anaesthetized rats

R Tabrizchi - Naunyn-Schmiedeberg's Archives of Pharmacology, 2001 - Springer
… The fact that an increase in dP/dt during infusion with noradrenaline did not result in an
increase in cardiac output in TNFα-treated rats would suggest that an increase in arterial re- …

… OF AN ANTI-TUMOR NECROSIS FACTOR α MONOCLONAL ANTIBODY IN PATIENTS WITH SEVERE SEPSIS: EFFECTS ON THE CARDIOVASCULAR SYSTEM …

P Boekstegers, S Weidenhöfer, R Zell, G Pilz, E Holler… - Shock, 1994 - journals.lww.com
… -tumor necrosis factor a (TNFa)-antibody (MAK 195F) on cytokine leveis and the cardiovascular
system … of mortality and improvement of the cardiovascular system, await the results of …

TNF-α: A Benificial or Harmful Pathogenic Cytokine in Cardiovascular System

S Dhiman, I Kumar, P Palia, S Jamwal… - Journal of Drug Delivery …, 2021 - jddtonline.info
… However, TNF-α is still controversial for its beneficial or harmful effects for cardiovascular
system. This review includes evaluation of possible role of TNF-α in cardiovascular system

Role of TNF-α in vascular dysfunction

H Zhang, Y Park, J Wu, XP Chen, S Lee, J Yang… - Clinical …, 2009 - portlandpress.com
… anti-TNF-α treatment in vascular diseases and cardiovascular … Is it time to revisit antagonism
of TNF-α in cardiovascular … development of selective TNF-α antagonists with therapeutic …

TNFα in atherosclerosis, myocardial ischemia/reperfusion and heart failure

P Kleinbongard, G Heusch, R Schulz - Pharmacology & therapeutics, 2010 - Elsevier
… The formation and release of TNFα and its downstream signal transduction … subtypes is
characterized, with special emphasis on the cardiovascular system. … Tumor necrosis factor α

Apoptosis in the cardiovascular system

MR Bennett - Heart, 2002 - heart.bmj.com
… the tumour necrosis receptor family (TNF-R), such as Fas (CD95), TNF-R1, or death receptors
… adapter proteins (Fas-FADD, TNF-R1-TRADD, etc) through protein:protein interactions 12, …