The role of glial reaction and inflammation in Parkinson's disease
…, E Rousselet, S Hunot, A Hartmann… - Annals of the New …, 2003 - Wiley Online Library
… In conclusion, the data reviewed here suggest an involvement of the glial reaction and
inflammatory processes in the progression of neuronal degeneration in parkinsonian syndromes. …
inflammatory processes in the progression of neuronal degeneration in parkinsonian syndromes. …
Glial reactions in Parkinson's disease
PL McGeer, EG McGeer - Movement disorders: official journal …, 2008 - Wiley Online Library
… Since glia are the main generators of these processes, the possibility that PD may be caused
by glial dysfunction needs to be considered. This review concentrates on glial reactions in …
by glial dysfunction needs to be considered. This review concentrates on glial reactions in …
Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson's disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling …
MF Sun, YL Zhu, ZL Zhou, XB Jia, YD Xu… - Brain, behavior, and …, 2018 - Elsevier
… whether brain glia are activated when fecal SCFAs increase abnormally. Thus, we
measured the interactional activities between dopaminergic neurons and brain glia, including …
measured the interactional activities between dopaminergic neurons and brain glia, including …
Glial cells and inflammation in Parkinson's disease: a role in neurodegeneration?
EC Hirsch, S Hunot, P Damier… - Annals of neurology, 1998 - Wiley Online Library
… In this context, the glial reaction observed in neurodegenerative … that glial cells are involved
in the selective de generation of dopaminergic neurons by inducing an in flammatory reaction…
in the selective de generation of dopaminergic neurons by inducing an in flammatory reaction…
Role of tumor necrosis factor-α in neuronal and glial apoptosis after spinal cord injury
YB Lee, TY Yune, SY Baik, YH Shin, S Du, H Rhim… - Experimental …, 2000 - Elsevier
We investigated the role of tumor necrosis factor (TNF)-α in the onset of neuronal and glial …
, an intense immunoreactivity to TNF-α was observed in neurons and glial cells in the lesion …
, an intense immunoreactivity to TNF-α was observed in neurons and glial cells in the lesion …
Glial neuronal signaling in the central nervous system
E Hansson, L Rönnbäck - The FASEB Journal, 2003 - Wiley Online Library
… Under physiological conditions, microglia synthesize and release trophic factors; however,
as soon as there is a functional disturbance of any kind in the CNS, microglia react, proliferate…
as soon as there is a functional disturbance of any kind in the CNS, microglia react, proliferate…
Honokiol inhibits the inflammatory reaction during cerebral ischemia reperfusion by suppressing NF-κB activation and cytokine production of glial cells
P Zhang, X Liu, Y Zhu, S Chen, D Zhou, Y Wang - Neuroscience letters, 2013 - Elsevier
… on TNF-α in glial cells (Fig. 4A) and LPS-induced TNF-α elevation in coculture glial cells was
… However, honokiol significantly suppressed LPS-induced TNF-α elevation in coculture glial …
… However, honokiol significantly suppressed LPS-induced TNF-α elevation in coculture glial …
Acute lipopolysaccharide-mediated injury in neonatal white matter glia: role of TNF-α, IL-1β, and calcium
C Sherwin, R Fern - The Journal of Immunology, 2005 - journals.aai.org
… We report that TNF-α and IL-1β directly evoke acute cell death in RON glia, with the degree
… not found to cause acute glial cell death. Combined IL-1β, IL-6, and TNF-α exposure did not …
… not found to cause acute glial cell death. Combined IL-1β, IL-6, and TNF-α exposure did not …
Cascading glia reactions: a common pathomechanism and its differentiated control by cyclic nucleotide signaling
P Schubert, T Morino, H Miyazaki… - Annals of the New …, 2000 - Wiley Online Library
… Specifically, the LPS-induced release of TNF-α and IL-1β from cultivated rat microglia was
… This means that those cytokines, which tend to stimulate a cascading glial reaction, are …
… This means that those cytokines, which tend to stimulate a cascading glial reaction, are …
TNF-α and TNF-α receptor type 1 upregulation in glia and neurons after peripheral nerve injury: studies in murine DRG and spinal cord
S Ohtori, K Takahashi, H Moriya, RR Myers - Spine, 2004 - journals.lww.com
… study was to evaluate changes in tumor necrosis factor-α (TNF-α) and TNF-α receptor 1 (p55
receptor) using double fluorescent immunohistochemistry in glial and neural cells in the …
receptor) using double fluorescent immunohistochemistry in glial and neural cells in the …
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