… SOCS3 in RANKL-induced osteoclasts. We therefore … that TNF-α-induced osteoclasts also
express SOCS3 and TGF-β strongly up-regulates this. Moreover, TNF-α-induced osteoclast …

… 6C), providing further support that iguratimod inhibited TNF-α-induced osteoclastogenesis …
TNF-α-induced osteoclastogenesis, we examined the effects of iguratimod on TNF-α-induced …

… NF-κB activation is indispensable to TNF-α-amplified osteoclast formation Next, we explored
the molecular clues of TNF-α in RANKL-induced osteoclasts formation. Addition of TNF-α …

… sham control mice and PGRN strongly induced osteoclastogenesis in the presence of Receptor
… of PGRN on TNF-α-induced osteoclastogenesis and osteoblastic differentiation in vitro. …

… This process is mediated largely by local production of proinflammatory cytokines, such as
tumor necrosis factor α (TNFα) and interleukin 1 (IL-1) [1], [2]. These cytokines may act directly …

… Over-activated osteoclasts derived from myeloid or … the effect of IL-35 on TNF-α-induced
osteoclastogenesis. In the presence of IL-… The effects of IL-35 on TNF-α-induced apoptosis were …

… in TNF‐α–induced osteoclastogenesis by modulating the sensitivity of osteoclast progenitors
to TNF‐α… The data suggest that inhibition of SH3BP2 expression in osteoclast progenitors …

… To further define the role of RANK signaling in TNFα‐induced osteoclastogenesis in vivo,
we crossed the TNF‐Tg mice with RANK knockout mice (RANK −/− ). These mice (…

… We propose that circulating OCPs enter the synovium and are induced to become osteoclasts
by RANKL expressed by synoviocytes (outside-in). In parallel, OCPs traverse endothelial …

… However, the roles of PKR in the TNF-α-induced osteoclast differentiation have not been
investigated. In this study, we examined the roles of PKR in the TNF-α-induced osteoclast …