… in inducing osteoclast differentiation and activation [25, 26]. TNF-α and RANKL influence each
other in osteoclast … have hypothesized that TNF-α may induce osteoclastogenesis even in …

… In this current study GM-OP and TNF-OP proved to be able to survive as osteoclast precursors
without the resorption ability. In other words, they were thought to wait for other signal than …

… plays a significant role in directly and indirectly promoting osteoclastogenesis. … inducing
RANKL expression (30). Similarly, IL-1β indirectly promotes TNF-αinduced osteoclastogenesis …

… TNF-α, the osteoclastogenesis was assessed. RANKL and TNF-α induced osteoclastogenesis
… inhibition of RANKL and TNF-α reduced the IL-17–induced osteoclastogenesis. A bone-…

… In contrast, LPS does not substantially enhance osteoclast proliferation in mice … -induced
osteoclastogenesis is mediated by TNF in vivo via this receptor. Thus, therapy targeting TNF and…

… Furthermore, the effect of the pro-inflammatory cytokines TNF-α, IL-17, IL-6, IL-1β, and IL-23
on osteoclastogenesis in vitro demonstrated that they have specific characteristic …

… TNFα stimulation induced osteoclast formation in the absence of … not induce osteoclast
formation in the absence of sRANKL, but both TNFα and IL1β significantly enhanced osteoclast …

… In this review, we summarize the involvement of these factors in inducing osteoclastogenesis
in vitro. Although these factors weakly induce osteoclast formation, they may play a major …

… This result indicates that TNF-α-induced osteoclastogenesis is the result of a coupling …
while the osteoclast induction by TNF-α was established, their effects on osteoclast function …

… TNF-α/IL-6-induced osteoclastogenesis, we studied the protein levels of NFATc1 in osteoclasts
… miR-124 mimic inhibits TNF-α/IL-6-induced NFATc1 translation, but not its transcription. …