[PDF][PDF] TNF-α induces a pro-inflammatory phenotypic shift in monocytes through ACSL1: relevance to metabolic inflammation

F Al-Rashed, Z Ahmad, MA Iskandar… - Cell Physiol …, 2019 - cellphysiolbiochem.com
… resulting from TNF-αTNF-α-associated inflammatory polarization in monocytes is an ACSL1
dependent process, which indicates its central role in TNF-α-driven metabolic inflammation. …

TNFα autocrine feedback loops in human monocytes: The pro‐and anti‐inflammatory roles of the TNFα receptors support the concept of selective TNFR1 blockade …

JM Gane, RA Stockley, E Sapey - Journal of immunology …, 2016 - Wiley Online Library
… of TNF-α and central to many TNF-α driven diseases. We hypothesised that TNF-α has pro-
and anti-inflammatory effects on monocytes, … Monocytes were isolated from healthy human …

CD14+ CD16+ monocytes in coronary artery disease and their relationship to serum TNF-α levels

A Schlitt, GH Heine, S Blankenberg… - Thrombosis and …, 2004 - thieme-connect.com
Monocytes play a central role in the inflammatory disease … + monocytes are considered
proinflammatory monocytes, as … as TNF-α, and are elevated in various inflammatory diseases.We …

Integrin regulation of leukocyte inflammatory functions. CD11b/CD18 enhancement of the tumor necrosis factor-alpha responses of monocytes.

S Fan, TS Edgington - Journal of immunology (Baltimore, Md.: 1950 …, 1993 - journals.aai.org
… , wasting, and diverse forms of inflammation, TNF-a also activates a … in inflammatory disease
(21). We now explore a postulated role of CD 1 1 b/CD 18 as a cognate element in the TNF-…

Exercise training-induced lowering of inflammatory (CD14+ CD16+) monocytes: a role in the anti-inflammatory influence of exercise?

KL Timmerman, MG Flynn, PM Coen… - Journal of Leucocyte …, 2008 - academic.oup.com
… the inflammatory potential of the monocyte pool as a whole [ 22 , 23 ]. Researchers discovered
recently that the circulating, inflammatory monocytemonocytes, inflammatory monocytes

Monocyte homeostasis and the plasticity of inflammatory monocytes

AJ Mitchell, B Roediger, W Weninger - Cellular immunology, 2014 - Elsevier
… under infectious and/or inflammatory conditions and focus on the plastic nature of inflammatory
monocytes. This plasticity allows inflammatory monocytes to tailor their phenotype to the …

Cytokines, acute‐phase proteins, and hormones: IL‐1 and TNFα production in contact‐mediated activation of monocytes by T lymphocytes

D Burger, JM DAYER - Annals of the New York Academy of …, 2002 - Wiley Online Library
inflammatory cells, including monocytes and lymphocytes. T cells appear to play an important
role in triggering the inflammation … β have predominantly anti-inflammatory effects and IFNγ …

Cryptosporidium parvum increases intestinal permeability through interaction with epithelial cells and IL‐1β and TNFα released by inflammatory monocytes

T de Sablet, L Potiron, M Marquis… - Cellular …, 2016 - Wiley Online Library
… + inflammatory monocytes to the subepithelial space. TNFα and IL-1β produced by inflammatory
monocytes … that both the parasite and inflammatory monocytes contribute to the loss of …

Distinct responses of monocytes to Toll‐like receptor ligands and inflammatory cytokines

C Farina, D Theil, B Semlinger… - International …, 2004 - academic.oup.com
… of monocytes to TLR‐ligands and inflammatory cytokines, we have identified a monocyte
activation marker, SLAM, which differs in its inducibility from other monocyte activation markers. …

Role of increased production of monocytes TNF-α, IL-1β and IL-6 in psoriasis: relation to focal infection, disease activity and responses to treatments

H Mizutani, Y Ohmoto, T Mizutani, M Murata… - Journal of …, 1997 - Elsevier
… To evaluate the immunological function of peripheral blood monocytes (PBMC) in psoriasis,
we measured spontaneous production of the inflammatory cytokines, TNF-c(, IL-lp and IL-6 …