Tumor necrosis factor-α signaling in macrophages

N Parameswaran, S Patial - Critical Reviews™ in Eukaryotic …, 2010 - dl.begellhouse.com
… variations of the signaling mediators for TNFαinduced signaling pathways, depending on …
Several studies suggest that antiTNFα therapeutics may work by affecting signaling pathways

The role of TNF-α signaling pathway on COX-2 upregulation and cognitive decline induced by β-amyloid peptide

R Medeiros, CP Figueiredo, P Pandolfo… - Behavioural brain …, 2010 - Elsevier
pathways affected following its activation. Therefore, in the present study we evaluated the
role of TNF-α signaling pathway … of several TNF-α-dependent intracellular pathways that have …

The role of tumor necrosis factor alpha (TNF-α) in autoimmune disease and current TNF-α inhibitors in therapeutics

D Jang, AH Lee, HY Shin, HR Song, JH Park… - International journal of …, 2021 - mdpi.com
… induces the proliferation and anti-apoptosis of keratinocytes via the NF-κB signal pathway,
eventually leading to the formation of microabscess by enhancing the recruitment of …

Connecting TNF-α signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by …

R Medeiros, RDS Prediger, GF Passos… - Journal of …, 2007 - Soc Neuroscience
… between tumor necrosis factor-α (TNF-α)-related signaling pathways and … TNF-α or iNOS
reduced the cognitive deficit evoked by Aβ 1–40 in mice. Similar results were obtained in TNF-α

Altered expression of TNF-α signaling pathway proteins in systemic lupus erythematosus

LJ Zhu, C Landolt-Marticorena, T Li, X Yang… - The Journal of …, 2010 - jrheum.org
TNF-α signaling in SLE patients favoring cellular activation, as opposed to proapoptotic
pathways… these molecules might arise in response to TNF-α signaling. To assess this possibility, …

Microtubule-mediated NF-κB activation in the TNF-α signaling pathway

RW Jackman, MG Rhoads, E Cornwell… - Experimental cell …, 2009 - Elsevier
… of TNF-α-induced NF-κB signalTNF-α signaling. We present a model for the action of
microtubules in regulating NF-κB induction possibly at the activation complex of the TNF

[HTML][HTML] The UV response of the skin: a review of the MAPK, NFκB and TNFα signal transduction pathways

V Muthusamy, TJ Piva - Archives of dermatological research, 2010 - Springer
… by a network of signalling pathways and in turn may trigger these pathways in an autocrine
or … UV is a stimulus that activates multiple signalling cascades, but how these pathways are …

The effects of protein malnutrition on the TNF-RI and NF-κB expression via the TNF-α signaling pathway

DC de Oliveira, AA Hastreiter, AS Mello… - Cytokine, 2014 - Elsevier
… and given that the NF-κB pathway, which is activated by TNF-α via TNF-RI, is important for the
… proteins involved in the NF-κB signaling pathway triggered by TNF-RI in murine peritoneal …

Investigations into the analysis and modeling of the TNFα-mediated NF-κB-signaling pathway

KH Cho, SY Shin, HW Lee, O Wolkenhauer - Genome Research, 2003 - genome.cshlp.org
… In this study, we propose a system-theoretic approach to the analysis and quantitative
modeling of the TNFα-mediated NF-κB-signaling pathway. Tumor necrosis factor α (TNFα) is a …

Tumor necrosis factor alpha signaling pathway and apoptosis in pancreatic β cells

…, N Hashimoto, H Makino, Y Saito, A Kanatsuka - Metabolism, 1999 - Elsevier
… Here, we investigate a role for tumor necrosis factor alpha (TNF-~) in the apoptosis of I~
cells. Using the ribonuclease (RNase) protection assay and the reverse transcriptase-…