Plasma extracellular vesicles bearing PD-L1, CD40, CD40L or TNF-RII are significantly reduced after treatment of AIDS-NHL
LE Martínez, S Lensing, D Chang, LI Magpantay… - Scientific reports, 2022 - nature.com
… We found that plasma levels of EVs expressing PD-L1, CD40, CD40L or TNF-RII were …
of EVs bearing PD-L1, compared to those with Burkitt’s lymphoma. CD40, CD40L and TNF-RII-…
of EVs bearing PD-L1, compared to those with Burkitt’s lymphoma. CD40, CD40L and TNF-RII-…
Increased intratumoral mast cells foster immune suppression and gastric cancer progression through TNF-α-PD-L1 pathway
Y Lv, Y Zhao, X Wang, N Chen, F Mao, Y Teng… - … for immunotherapy of …, 2019 - Springer
… 3f) and a high expression of TNF-α receptor II (TNFRII) on mast cells (Additional file 8: … -derived
TNF-α in PD-L1 induction on mast cells, we added neutralizing antibody against TNF-α …
TNF-α in PD-L1 induction on mast cells, we added neutralizing antibody against TNF-α …
Inflammation-Driven Regulation of PD-L1 and PD-L2, and Their Cross-Interactions with Protective Soluble TNFα Receptors in Human Triple-Negative Breast Cancer
T Baram, N Oren, N Erlichman, T Meshel… - Cancers, 2022 - mdpi.com
… PD-L1 down-regulated the cell-derived levels of sTNFR1 and sTNFR2, the soluble receptors
of tumor necrosis factor … of PD-L1-mediated tumor progression in which PD-L1 prevents the …
of tumor necrosis factor … of PD-L1-mediated tumor progression in which PD-L1 prevents the …
[HTML][HTML] Combination cancer immunotherapy targeting TNFR2 and PD-1/PD-L1 signaling reduces immunosuppressive effects in the microenvironment of pancreatic …
X Zhang, M Lao, J Xu, Y Duan, H Yang… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
… of TNF-α. The anti-TNFR1 antibodies did not affect the level of the PD-L1 protein in TNF-α-…
antibodies abolished the TNF-α-induced upregulation of PD-L1 expression in pancreatic …
antibodies abolished the TNF-α-induced upregulation of PD-L1 expression in pancreatic …
Anti-tumor necrosis factor receptor 2 antibody combined with anti-Pd-L1 therapy exerts robust antitumor effects in breast cancer
Q Fu, Q Shen, J Tong, L Huang, Y Cheng… - Frontiers in Cell and …, 2021 - frontiersin.org
… In this study, we demonstrated that tumor necrosis factor receptor 2 (TNFR2) is highly …
Furthermore, we demonstrated that anti-TNFR2 antibody in combination with anti-PD-L1 exhibited …
Furthermore, we demonstrated that anti-TNFR2 antibody in combination with anti-PD-L1 exhibited …
Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren's syndrome.
M Kobayashi, S Kawano, S Hatachi… - The Journal of …, 2005 - jrheum.org
… that PDL1 expression cannot be induced by IL-1ß, in contrast to that of CD80/86. These results
suggest the possibility that PD-L1 … TNF-α or IL-1ß stimulation, while they expressed PD-L1 …
suggest the possibility that PD-L1 … TNF-α or IL-1ß stimulation, while they expressed PD-L1 …
TNFR2 expression predicts the responses to immune checkpoint inhibitor treatments
… Interestingly, it was reported that TNF could upregulate PD-L1 expression in pancreatic
cancer cells through TNFR2 signaling, and consequently induced PD-1/PD-L1-mediated …
cancer cells through TNFR2 signaling, and consequently induced PD-1/PD-L1-mediated …
[HTML][HTML] … PD-L1–positive regulatory T cells and PD-1–positive CD8-positive T cells define the response of different subsets of non–small cell lung cancer to PD-1/PD …
SP Wu, RQ Liao, HY Tu, WJ Wang, ZY Dong… - Journal of Thoracic …, 2018 - Elsevier
… TNF-α– and IFN-γ–producing CD8 T cells in PD-1 … TNF-α–producing CD8 T cells in PD-1
hi PD-L1 hi to a greater extent than in PD-1 hi PD-L1 lo , PD-1 lo PD-L1 hi , and PD-1 lo PD-L1 …
hi PD-L1 hi to a greater extent than in PD-1 hi PD-L1 lo , PD-1 lo PD-L1 hi , and PD-1 lo PD-L1 …
Regulation of TCR-mediated T cell activation by TNF-RII
RM Aspalter, MM Eibl, HM Wolf - Journal of Leucocyte Biology, 2003 - academic.oup.com
… the role of tumor necrosis factor receptor II (TNF-RII) in human … interaction of TNF-α with
TNF-RII but not TNF-RI is directly … , TNF-RII), and secretion of cytokines such as interferon-γ and …
TNF-RII but not TNF-RI is directly … , TNF-RII), and secretion of cytokines such as interferon-γ and …
PD-1/PD-L and autoimmunity: a growing relationship
… Adalimumab (a human anti-tumor necrosis factor monoclonal antibody) has been effective
at … It was demonstrated that treatment with anti-TNF-α in RA patients was correlated with an …
at … It was demonstrated that treatment with anti-TNF-α in RA patients was correlated with an …
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