Tobramycin solution for inhalation in cystic fibrosis patients: a review of the literature

JK Hagerman, SA Knechtel… - Expert Opinion on …, 2007 - Taylor & Francis
… binding of tobramycin to mucin in the sputum of cystic fibrosis patients, … It is also important to
note that cystic fibrosis patients are … with respect to tobramycin MIC. One study demonstrated …

Reduced mortality in cystic fibrosis patients treated with tobramycin inhalation solution

GS Sawicki, JE Signorovitch, J Zhang… - Pediatric …, 2012 - Wiley Online Library
… Though tobramycin inhalation solution has been used for … and reduce exacerbations in
patients with cystic fibrosis (CF), … of tobramycin inhaled solution and mortality in patients with CF …

Treatment with tobramycin solution for inhalation reduces hospitalizations in young CF subjects with mild lung disease

TD Murphy, RD Anbar, LA Lester, SZ Nasr… - Pediatric …, 2004 - Wiley Online Library
… of tobramycin solution for inhalation (TSI; TOBI®, Chiron Corp.) on lung function decline rate
in 400 young persons with cystic fibrosis … of inhaled tobramycin in patients with cystic fibrosis

A pilot study of the safety and efficacy of tobramycin solution for inhalation in patients with severe bronchiectasis

P Scheinberg, E Shore, PC-TNDS-008 study group - Chest, 2005 - Elsevier
patients is variable, and based both on the infecting species and individual clinician
experience. Tobramycin solution … of pseudomonal infections in patients with cystic fibrosis.7, 8 A …

Long-term safety and efficacy of tobramycin in the management of cystic fibrosis

E Vázquez-Espinosa, RM Girón… - … and clinical risk …, 2015 - Taylor & Francis
… an inhaled parenteral solution. Subsequently, a specific tobramycin inhalation solution was
… of two inhaled tobramycin solutions in cystic fibrosis patients with Pseudomonas aeruginosa …

Efficacy of aerosolized tobramycin in patients with cystic fibrosis

BW Ramsey, HL Dorkin, JD Eisenberg… - … England Journal of …, 1993 - Mass Medical Soc
… Direct aerosol delivery of aminoglycosides such as tobramycin to the lower airways of
patients with cystic fibrosis may control infection with Pseudomonas aeruginosa and improve …

Treatment with tobramycin solution for inhalation in bronchiectasis patients with Pseudomonas aeruginosa

LA Couch - Chest, 2001 - Elsevier
tobramycin solution for inhalation (TSI) administered twice daily for 4 weeks in 74 bronchiectasis
patients colonized … Data from a trial of TSI in cystic fibrosis (CF) patients 6 are shown for …

[HTML][HTML] Tobramycin safety and efficacy review article

C Schwarz, G Taccetti, PR Burgel, S Mulrennan - Respiratory medicine, 2022 - Elsevier
Fibrosis Foundation (CFF) guidelines strongly recommend eradication therapy with tobramycin
inhaled solution (… placebo in 520 patients with a diagnosis of cystic fibrosis and a positive …

A Formulation of Aerosolized Tobramycin (Bramitob®) in the Treatment of Patients with Cystic Fibrosis and Pseudomonas aeruginosa Infection: A Double-Blind …

A Chuchalin, E Csiszér, K Gyurkovics, MT Bartnicka… - Pediatric Drugs, 2007 - Springer
… Chronic infection with Pseudomonas aeruginosa in patients with cystic fibrosis (CF) causes
… the efficacy and tolerability of a tobramycin highly concentrated solution for inhalation (TSI) […

[HTML][HTML] Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: the EAGER trial

MW Konstan, PA Flume, M Kappler, R Chiron… - … of Cystic Fibrosis, 2011 - Elsevier
… and improve patient convenience and satisfaction. We evaluated the safety, efficacy and
convenience of tobramycin inhalation powder (TIP™) versus tobramycin inhalation solution (TIS…