[HTML][HTML] Appropriate use of tocilizumab in COVID-19 infection

Ş Keske, S Tekin, B Sait, P İrkören, M Kapmaz… - International Journal of …, 2020 - Elsevier
… effectiveness and optimum use of tocilizumab (TCZ) treatment … total duration of hospitalization
after administration of TCZ was … Comparison of the patients who were given tocilizumab

[HTML][HTML] Tocilizumab for treatment of patients with severe COVID–19: A retrospective cohort study

T Kewan, F Covut, MJ Al–Jaghbeer, L Rose… - …, 2020 - thelancet.com
… ] and may provide clinical benefit for selected COVID–19 patients with high inflammatory
biomarkers. We hereby report our experience with using tocilizumab in hospitalized patients

What about tocilizumab? A retrospective study from a NYC Hospital during the COVID-19 outbreak

M Mehta, LJ Purpura, TH McConville, MJ Neidell… - PLoS …, 2021 - journals.plos.org
… Additionally, there is concern that exposure to tocilizumab may lead to increased risk of …
We hypothesized that patients with severe COVID-19 who received tocilizumab would have …

Tocilizumab in hospitalized patients with COVID-19: a meta analysis of randomized controlled trials

V Selvaraj, MS Khan, C Bavishi, K Dapaah-Afriyie… - Lung, 2021 - Springer
… and need for mechanical ventilation, in hospitalized patients with COVID-19 infection …
tocilizumab therapy in hospitalized COVID-19 patients and strengthen the concept that tocilizumab

Early outcomes of tocilizumab in adults hospitalized with severe COVID-19-The Vall d'Hebron COVID-19 prospective cohort study

A Sánchez-Montalvá, J Sellarés-Nadal… - MedRxiv, 2020 - medrxiv.org
… of patients with COVID-19 receiving tocilizumab for the treatment of inflammatory-related
lung injury. Time from lung injury onset to tocilizumab administration may be critical to patient

Administration timing and efficacy of tocilizumab in patients with COVID-19 and elevated IL-6

P Li, Z Lu, Q Li, Z Wang, Y Guo, C Cai… - Frontiers in molecular …, 2021 - frontiersin.org
… , which suggests that later administration of TCZ in critically ill patients with evidence of an …
Remarkably, of the 12 patients who died during the TCZ treatment, 58.3% patients had higher …

Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

DJ Dhasmana… - …, 2021 - research-repository.st-andrews.ac …
… Background In this study, we aimed to evaluate the effects of tocilizumab in adult patients
admitted to hospital with COVID-19 with both hypoxia and systemic inflammation. …

Tocilizumab and steroid treatment in patients with COVID-19 pneumonia

M Mikulska, LA Nicolini, A Signori, A Di Biagio… - Plos one, 2020 - journals.plos.org
… We started using tocilizumab in patients with respiratory failure, and … administration of
methylprednisolone treatment, followed in more severe cases by the administration of tocilizumab. …

[HTML][HTML] Tocilizumab versus baricitinib in hospitalized patients with severe COVID-19: an open label, randomized controlled trial

T Karampitsakos, O Papaioannou, P Tsiri… - Clinical Microbiology …, 2023 - Elsevier
… of administration, drug–drug interactions, and metabolism, we aimed to investigate whether
baricitinib was non-inferior to tocilizumab in hospitalized patients with severe COVID-19. …

[HTML][HTML] Optimal use of tocilizumab for severe and critical COVID-19: a systematic review and meta-analysis

CW Nugroho, SD Suryantoro, Y Yuliasih… - …, 2021 - ncbi.nlm.nih.gov
patients enrolled in the tocilizumab group and 6160 patients in the SOC group, were included
in this meta-analysis. Compared to the SOC, tocilizumab … no difference in hospital length of …