[HTML][HTML] Tocilizumab in patients hospitalised with COVID-19 pneumonia: Efficacy, safety, viral clearance, and antibody response from a randomised controlled trial …
IO Rosas, N Bräu, M Waters, RC Go, A Malhotra… - …, 2022 - thelancet.com
… -CoV-2 viral load, standard-of-care medications, and patient … the effect of tocilizumab on viral
clearance and host immune … with tocilizumab did not delay SARS-CoV-2 viral clearance or …
clearance and host immune … with tocilizumab did not delay SARS-CoV-2 viral clearance or …
[HTML][HTML] Impact of interleukin-6 blockade with tocilizumab on SARS-CoV-2 viral kinetics and antibody responses in patients with COVID-19: A prospective cohort study
… viral clearance is delayed in patients receiving tocilizumab, this effect is mainly driven by
the initial viral … Our results can also be extrapolated to patients receiving tocilizumab for …
the initial viral … Our results can also be extrapolated to patients receiving tocilizumab for …
[HTML][HTML] Tocilizumab in patients with severe COVID-19: a retrospective cohort study
G Guaraldi, M Meschiari, A Cozzi-Lepri… - The Lancet …, 2020 - thelancet.com
… storm, treatment with tocilizumab appeared to have clinical … higher in patients without
tocilizumab than in the tocilizumab group (72… effect of tocilizumab compared with standard of care. …
tocilizumab than in the tocilizumab group (72… effect of tocilizumab compared with standard of care. …
[HTML][HTML] Utilizing tocilizumab for the treatment of cytokine release syndrome in COVID-19
A Hassoun, ED Thottacherry, J Muklewicz… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
… There are concerns regarding the risk of infection as well as theoretically delaying viral
clearance [2,5]. Our patients were screened for … Viral clearance was not assessed in our patients. …
clearance [2,5]. Our patients were screened for … Viral clearance was not assessed in our patients. …
Determinants of prolonged viral RNA shedding in hospitalized patients with SARS-CoV-2 infection
FC Dezza, A Oliva, F Cancelli, G Savelloni… - … and infectious disease, 2021 - Elsevier
… Univariate analyses showed that age, male gender, receiving corticosteroids, receiving
tocilizumab, ICU admission, low albumin and NLR ratio were associated with late viral clearance…
tocilizumab, ICU admission, low albumin and NLR ratio were associated with late viral clearance…
Short‐course tocilizumab increases risk of hepatitis B virus reactivation in patients with rheumatoid arthritis: a prospective clinical observation
LF Chen, YQ Mo, J Jing, JD Ma… - … journal of rheumatic …, 2017 - Wiley Online Library
… in RA patients with chronic HBV infection, but in this study patients remained asymptomatic
and had a benign outcome after antiviral treatment. To identify the exact risk of TCZ on HBV …
and had a benign outcome after antiviral treatment. To identify the exact risk of TCZ on HBV …
[HTML][HTML] Early use of low dose tocilizumab in patients with COVID-19: a retrospective cohort study with a complete follow-up
N De Rossi, C Scarpazza, C Filippini, C Cordioli… - …, 2020 - thelancet.com
… of tocilizumab patients as compared to controls (multivariate HR for death: 0.057; 95% CI
= 0.017- 0.187, p < 0.001, Fig. 1). The data revealed that the risk of death increases by 6% for …
= 0.017- 0.187, p < 0.001, Fig. 1). The data revealed that the risk of death increases by 6% for …
[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients
KL Zheng, Y Xu, YF Guo, L Diao, XY Kong… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… may have a negative effect on viral clearance [29]. In the present … tocilizumab-treated and
conventionally treated patients (22.4 vs. 18.8, P=0.184). The dose and frequency of tocilizumab …
conventionally treated patients (22.4 vs. 18.8, P=0.184). The dose and frequency of tocilizumab …
Tocilizumab for treatment of mechanically ventilated patients with COVID-19
EC Somers, GA Eschenauer, JP Troost… - Clinical Infectious …, 2021 - academic.oup.com
… of viral myocarditis [15] and candidemia [16] with tocilizumab … IL-6 blockade with tocilizumab
is considered for patients with … of usage occurring in patients requiring mechanical ventilation…
is considered for patients with … of usage occurring in patients requiring mechanical ventilation…
Tocilizumab in hospitalized patients with COVID‐19: clinical outcomes, inflammatory marker kinetics, and safety
JA Hill, MP Menon, S Dhanireddy… - Journal of medical …, 2021 - Wiley Online Library
… control for many viral infections, but overproduction of IL-6 may be detrimental to viral
clearance and survival. Results from a randomized controlled trial indicate that tocilizumab did not …
clearance and survival. Results from a randomized controlled trial indicate that tocilizumab did not …
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