Tolerance and Resistance of Pseudomonas aeruginosa Biofilms to Antimicrobial Agents—How P. aeruginosa Can Escape Antibiotics

O Ciofu, T Tolker-Nielsen - Frontiers in microbiology, 2019 - frontiersin.org
… nature of biofilm tolerance, we focus on specific classes of antibiotics, and describe
biofilm-associated antimicrobial tolerance mechanisms that play a role in tolerance to each of these …

Oxygen Limitation Contributes to Antibiotic Tolerance of Pseudomonas aeruginosa in Biofilms

G Borriello, E Werner, F Roe, AM Kim… - Antimicrobial agents …, 2004 - Am Soc Microbiol
The role of oxygen limitation in protecting Pseudomonas aeruginosa strains growing in
biofilms from killing by antibiotics was investigated in vitro. Bacteria in mature (48-h-old) colony …

Contribution of stress responses to antibiotic tolerance in Pseudomonas aeruginosa biofilms

PS Stewart, MJ Franklin, KS Williamson… - Antimicrobial agents …, 2015 - Am Soc Microbiol
… Insight into the mechanisms of biofilm antibiotic tolerance might lead to the … antibiotic
tolerance. Several studies have reported on the increased tolerance of Pseudomonas aeruginosa

Susceptibility and intrinsic tolerance of Pseudomonas aeruginosa to selected plant volatile compounds

SD Cox, JL Markham - Journal of Applied Microbiology, 2007 - academic.oup.com
… The two strains of P. aeruginosa included in the study exhibited intrinsic tolerance to all
compounds, with the exception of carvacrol and trans‐cinnamaldehyde. The protonophore …

RpoS-dependent stress tolerance in Pseudomonas aeruginosa

…, G Michel, A Lazdunski, P Williams… - …, 1999 - microbiologyresearch.org
Pseudomonas aeruginosa is able to persist during feast and famine in many different …
in conferring stress tolerance in P. aeruginosa towards a variety of environmental stresses. …

[HTML][HTML] The many antibiotic resistance and tolerance strategies of Pseudomonas aeruginosa

D Sindeldecker, P Stoodley - Biofilm, 2021 - Elsevier
Pseudomonas aeruginosa is a bacterial pathogen associated with a wide range of
infections and utilizes several strategies to establish and maintain infection including biofilm …

Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection

KL Tomlinson, YT Chen, A Junker, AC Urso, TWF Lung… - Cell Metabolism, 2023 - cell.com
Pseudomonas aeruginosa is a common cause of pulmonary … ; however, most hosts become
tolerant to the bacterial burden, … shift from inflammation to disease tolerance is promoted by …

Importance of the exopolysaccharide matrix in antimicrobial tolerance of Pseudomonas aeruginosa aggregates

L Goltermann, T Tolker-Nielsen - Antimicrobial Agents and …, 2017 - Am Soc Microbiol
… We then investigated antimicrobial tolerance of aggregates formed by the mucoid P.
aeruginosa mucA strain, which overproduces alginate because of an inactivating mutation in the …

Contributions of Antibiotic Penetration, Oxygen Limitation, and Low Metabolic Activity to Tolerance of Pseudomonas aeruginosa Biofilms to Ciprofloxacin and …

MC Walters III, F Roe, A Bugnicourt… - Antimicrobial agents …, 2003 - Am Soc Microbiol
… , and low metabolic activity in the tolerance of Pseudomonas aeruginosa in biofilms to killing
by … penetration, are correlated with antibiotic tolerance of this P. aeruginosa biofilm system. …

Pseudomonas aeruginosa biofilm infections: community structure, antimicrobial tolerance and immune response

M Rybtke, LD Hultqvist, M Givskov… - Journal of molecular …, 2015 - Elsevier
Pseudomonas aeruginosa biofilm in a chronic wound. The … and biofilm-associated antimicrobial
tolerance has come to the … on the biofilm model organism Pseudomonas aeruginosa. …