… the network structure of large-scale signaling systems. This analysis focuses on the structure
of signaling networks; future work will need to account for compartmentalization of signaling …

… networks [11]. Structural analysis will be particularly useful in large signaling networks, …
While we will focus on signaling networks, the methods can be easily applied to any kind of …

… that the topological information of signaling networks is highly … network topologies. Our
study is expected to provide a basis for utilizing the topological information of signaling networks …

… the simplest mathematical description of signaling networks. They have mainly been
applied to study global topological properties of networks containing up to several thousand …

… natural signaling networks and man-made networks. There … network topology whereas
much of the richness of biological behavior originates from kinetic properties coupled to topology…

… results obtained from this type of network analysis (ie, signaling pathways, key residues
for … by the topology of the network, with normally used determination of network edges by …

… reconstructions of signaling networks emerge, such scalable analyses will … systems properties
of signal transduction networks. … to study the topological properties of signaling networks ( …

… MetaboSignal also gives the option to build a tissue-specific signaling network that …
metabolic network is then merged with the signaling network to create the ‘MetaboSignal’ network …

… models is highly labor-intensive, the modeling of specific networks may be limited in
developing a broad understanding of the general properties of biological signaling networks. …

… from complex samples for further analysis. We first touch on mass spectrometry (MS)-based
methods and their application to signaling network analysis and then briefly describe …