Sliding windows and persistence: An application of topological methods to signal analysis
… We develop in this paper a theoretical framework for the topological study of time series
data. Broadly speaking, we describe geometrical and topological properties of sliding window …
data. Broadly speaking, we describe geometrical and topological properties of sliding window …
Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs
IN Melas, R Samaga, LG Alexopoulos… - PLoS computational …, 2013 - journals.plos.org
… Our goal is now to analyze and improve the consistency of an IG topology with respect to
a given set of experimental data. Central to all algorithms presented herein is the following …
a given set of experimental data. Central to all algorithms presented herein is the following …
Analysing the meta-interaction between pathways by gene set topological impact analysis
S Yan, X Chi, X Chang, M Tian - BMC genomics, 2020 - Springer
… The network clearly shows two distinct sub-networks: one is the signaling network of PI3K, …
is the adipogenesis gene set and the network of oxidative phosphorylation, fatty acid and …
is the adipogenesis gene set and the network of oxidative phosphorylation, fatty acid and …
Network topology inference from heterogeneous incomplete graph signals
… Different from the iterating approaches in [26] and [27], we wish to infer the network topology
through a … Therefore, it is important to explore more ways to improve the topology inference …
through a … Therefore, it is important to explore more ways to improve the topology inference …
Identifying disease-specific genes based on their topological significance in protein networks
Z Dezső, Y Nikolsky, T Nikolskaya, J Miller… - BMC systems …, 2009 - Springer
… generating shortest paths in protein signaling networks. The algorithm gives preference to
known signaling routes while reconstructing condition-specific networks. Recent work by Yu et…
known signaling routes while reconstructing condition-specific networks. Recent work by Yu et…
Centralities based analysis of complex networks
G Scardoni, C Laudanna - New frontiers in graph theory, 2012 - books.google.com
… reached in the topological analysis of networks, … signaling network with a very high average
closeness is more likely organizing functional units or modules, whereas a signaling network …
closeness is more likely organizing functional units or modules, whereas a signaling network …
Topological robustness analysis of protein interaction networks reveals key targets for overcoming chemotherapy resistance in glioma
H Azevedo, CA Moreira-Filho - Scientific reports, 2015 - nature.com
… Since cell signaling networks exhibit modular organization, we sought to identify … The
network topology analysis performed in this study revealed a set of central nodes associated to …
network topology analysis performed in this study revealed a set of central nodes associated to …
Identification of functional modules using network topology and high-throughput data
… Subnetwork hub analysis We hypothesized that the topology of the JACSs obtained by
MATISSE can provide clues to the key players in the regulation of the cell cycle machinery. To …
MATISSE can provide clues to the key players in the regulation of the cell cycle machinery. To …
An integrative thrombosis network: Visualization and topological analysis
… key nodes in a disease-specific network with important topological properties [13, 14]. …
thrombosis molecular network and analyze topological characteristics of the network from several …
thrombosis molecular network and analyze topological characteristics of the network from several …
Robustness and evolvability of the human signaling network
J Kim, D Vandamme, JR Kim, AG Munoz… - PLoS computational …, 2014 - journals.plos.org
… the mutational robustness of the biological networks since they only focused on topological
characteristics. Our results about the topological difference such as degree heterogeneity of …
characteristics. Our results about the topological difference such as degree heterogeneity of …