… Total homocysteine is therefore of value for the diagnosis and … Inaddition, total homocysteine
is an independent risk factor … the total homocysteine assay in the routine clinical chemistry …

… form, measurement of total homocysteine gave the necessary analytical sensitivity for
clinical applications such as detection of slightly elevated plasma homocysteine as a marker of …

… They demonstrated that an increase in plasma homocysteine of 1 μmol/L increases risk
by 6–7%. The odds ratio due to plasma total homocysteine above 18.6 μmol/L was 2.43 for …

… of total homocysteine (tHcy) in human plasma is defined as the sum of all the homocysteine
… Accurate determination of tHcy in human plasma is essential both for the clinical diagnosis …

… (30) A major advantage of measuring total homocysteine is that stored samples can be
analyzed because total homocysteine is not altered when samples are kept frozen, even for years…

… The aim of this study was to establish an accurate assay for total homocysteine in plasma
in order to determine this parameter in routine investigation in the assessment of vascular risk. …

… We addressed this problem in novel homocysteine assays as part of an European … Methods:
Two immunological methods for measurement of plasma total homocysteine (P-tHcy), the …

… total concentrations of the aminothiols homocysteine, cysteine, cysteinylglycine, and
glutathione in human plasma. Plasma aminothiols are reduced via incubation with tris-(2-…

… with increased concentrations of total homocysteine. The … of total homocysteine determinations
in clinical practice and in the research setting and on the relevance of total homocysteine …

… We report simultaneous clinical estimation of total Hcy and MMA with efficient clean-up,
sensitive and selective LC-MS/MS method. Efficient sample clean-up was achieved by a two-…