[HTML][HTML] Comparison of effectiveness and adverse effects of gefitinib, erlotinib and icotinib among patients with non‑small cell lung cancer: A network meta‑analysis

Y Liu, Y Zhang, G Feng, Q Niu… - Experimental and …, 2017 - spandidos-publications.com
… effectiveness and toxicity compared with gefitinib for the … of randomized controlled trials
from the Cochrane network was evaluated in terms of the presence or absence of a randomized

[HTML][HTML] … with gefitinib in advanced non-small cell lung cancer patients with epidermal growth factor receptor mutations: study protocol for a randomized controlled trial

XB Yang, W Wu, S Long, H Deng, ZQ Pan, WF He… - Trials, 2015 - Springer
… results in longer progression-free survival with less toxicity than gefitinib alone. A total of 70
gefitinib alone in patients with NSCLC [17]. In this study, we aim to assess whether gefitinib

Gefitinib

CR Culy, D Faulds - Drugs, 2002 - Springer
Toxicity Criteria; EHT = elevated hepatic transminases; * indicates that grade 3/4 toxicities
only occurred in patients receiving gefitinibclinical trials evaluating the efficacy of gefitinib in …

[HTML][HTML] A phase I trial of high dose gefitinib for patients with leptomeningeal metastases from non-small cell lung cancer

DM Jackman, LA Cioffredi, L Jacobs, F Sharmeen… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… , we had been able to administer gefitinib in doses as high as … toxicities that were observed
in previous phase I studies [17]. … clinical trials for leptomeningeal metastasis, this trial defined …

Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B

R Govindan, RA Kratzke, JE Herndon, GA Niehans… - … Cancer Research, 2005 - AACR
… effects of gefitinib are readily reversible on withdrawal of the compound. Both preclinical
and early clinical studies indicate that the toxicities associated with gefitinib are minimal (12). …

Effect of gefitinib challenge to initial treatment with non-small cell lung cancer

X Chen, W Li, X Hu, Y Geng, R Wang, Y Yin… - Biomedicine & …, 2011 - Elsevier
… This study was conducted to assess the efficacy and toxicity of gefitinib as first line treatment
in … be compared with standard treatment, and be verified by larger-specimen clinical trials. …

Gefitinib: phase II and III results in advanced non-small cell lung cancer

K Kelly, S Averbuch - Seminars in oncology, 2004 - Elsevier
… II trials of gefitinib monotherapy in patients with recurrent non-small cell lung cancer. Clinical
trials are … patients then receive gefitinib until disease progression or intolerable toxicity. …

[HTML][HTML] A phase II randomized multicenter trial of gefitinib plus FOLFIRI and FOLFIRI alone in patients with metastatic colorectal cancer

A Santoro, A Comandone, L Rimassa, C Granetti… - Annals of …, 2008 - Elsevier
… was started, there was a strong rationale to evaluate in a clinical study the … study with the
combination of gefitinib and FOLFIRI, we observed disappointing results in terms of toxicity, very …

Phase II trials of erlotinib or gefitinib in patients with recurrent meningioma

AD Norden, JJ Raizer, LE Abrey, KR Lamborn… - Journal of neuro …, 2010 - Springer
… 3 toxicities in 6 gefitinib patients and 3 grade 3 toxicities (1 … Because of pre-clinical data
suggesting that EGFR may drive … patients in phase II clinical trials of gefitinib and erlotinib for …

Phase II clinical trial of gefitinib for the treatment of chemonaive patients with advanced non-small cell lung cancer with poor performance status

NA Karim, S Musaad, A Zarzour… - Clinical Medicine …, 2014 - journals.sagepub.com
… received gefitinib 250 mg per day orally until disease progression or unacceptable toxicity
… Patients were considered evaluable if they received at least one dose of gefitinib and had …