Toxicological evaluation and risk assessment of chemical mixtures

FR Cassee, JP Groten, PJ Bladeren… - … Reviews in Toxicology, 1998 - Taylor & Francis
… 95% of the resources in toxicology is still devoted to studies of … assessment, hazard
identification, and risk assessment of … in this challenging vanguard of toxicology have increased. …

Toxicological evaluation of chemical mixtures

VJ Feron, JP Groten - Food and chemical toxicology, 2002 - Elsevier
… and risk assessment of chemical mixtures during the past 15 years, reviews today's state
of the art of mixture toxicology, and discusses future challenges for mixture toxicologists. …

The threshold of toxicological concern (TTC) in risk assessment

IC Munro, AG Renwick, B Danielewska-Nikiel - Toxicology letters, 2008 - Elsevier
… For individual chemicals with known toxicological profiles, there are established procedures
risks to humans. For non-genotoxic chemicals a conventional toxicological safety evaluation

[图书][B] Toxicological risk assessment for beginners

JA Torres, S Bobst - 2015 - Springer
… developed a panel presented at Society of Toxicology. After that, Springer approached us
… we presume to have a toxicology preparation, with the practical aspects of risk assessment. …

Critical effect sizes in toxicological risk assessment: a comprehensive and critical evaluation

S Dekkers, C de Heer, MAJ Rennen - Environmental Toxicology and …, 2001 - Elsevier
… A key issue in toxicological risk assessment is determining the effect level below which …
CESs for toxicological effect parameters commonly used in human risk assessment and includes …

Comparative toxicological evaluation of phthalate diesters and metabolites in Sprague-Dawley male rats for risk assessment

SJ Kwack, KB Kim, HS Kim, BM Lee - Journal of Toxicology and …, 2009 - Taylor & Francis
In order to comparatively assess the systemic toxicity and sperm parameters, nine phthalate
diesters, including di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), di-n-octyl …

Toxicological considerations, toxicity assessment, and risk management of inhaled nanoparticles

S Bakand, A Hayes - International journal of molecular sciences, 2016 - mdpi.com
… The necessity of toxicological risk assessment to human health should be emphasised as
… to assess the potential adverse outcomes of NPs. Toxicological risk assessment should be …

The threshold of toxicological concern concept in risk assessment

R Kroes, J Kleiner, A Renwick - Toxicological sciences, 2005 - academic.oup.com
risk assessment of compounds with known toxicological profiles. The traditional approach to
risk assessment … characterization, exposure assessment, and risk characterization, and data …

Re-evaluation of human-toxicological maximum permissible risk levels

AJ Baars, RMC Theelen, P Janssen, JM Hesse… - 2001 - rivm.openrepository.com
… These updates have been performed by the Centre for Substances and Risk Assessment
-evaluation is a pragmatic one in that use has been made of existing toxicological evaluations

A critical evaluation of safety (uncertainty) factors for ecological risk assessment

PM Chapman, A Fairbrother… - Environmental Toxicology …, 1998 - Wiley Online Library
Abstract Evaluation of environmental risks posed by potentially hazardous substances requires
achieving a balance between over‐ and underprotection, ie, between societal benefits …