General secretion pathway (eps) genes required for toxin secretion and outer membrane biogenesis in Vibrio cholerae
M Sandkvist, LO Michel, LP Hough… - Journal of …, 1997 - Am Soc Microbiol
… secretion for all -C to -N genes, except for the -H homolog, in Erwinia (38, 39). Other genes,
in addition to the eps genes … of the epsC to -N genes in E. coli does not lead to extracellular …
in addition to the eps genes … of the epsC to -N genes in E. coli does not lead to extracellular …
Characterization of the multimeric Eps complex required for cholera toxin secretion
M Sandkvist, M Bagdasarian, SP Howard - International journal of medical …, 2000 - Elsevier
… Following folding and assembly the toxin is then translocated … Secretion (Eps) machinery
encoded by at least 13 genes. Although the Eps proteins are believed to form a secretion …
encoded by at least 13 genes. Although the Eps proteins are believed to form a secretion …
Convergence of the secretory pathways for cholera toxin and the filamentous phage, CTXϕ
BM Davis, EH Lawson, M Sandkvist, A Ali… - Science, 2000 - science.org
… In previous studies of the additional eps genes, comparable incomplete complementation …
levels, suggesting that eps genes other than epsD are not required for phage secretion. To test …
levels, suggesting that eps genes other than epsD are not required for phage secretion. To test …
Exopolysaccharide protects Vibrio cholerae from exogenous attacks by the type 6 secretion system
J Toska, BT Ho, JJ Mekalanos - Proceedings of the …, 2018 - National Acad Sciences
… were altered in T6SS effector and EPS genes, we were able to directly measure the effect
of … In this study, we also observed that changes in EPS gene expression result in a …
of … In this study, we also observed that changes in EPS gene expression result in a …
Endochitinase Is Transported to the Extracellular Milieu by the eps-Encoded General Secretory Pathway ofVibrio cholerae
TD Connell, DJ Metzger, J Lynch… - Journal of …, 1998 - Am Soc Microbiol
… These results indicate that ChiA and cholera toxin have functionally similar extracellular … a
cloned endochitinase gene and establish that the protein encoded by that gene is secreted to …
cloned endochitinase gene and establish that the protein encoded by that gene is secreted to …
Mutations in the Extracellular Protein Secretion Pathway Genes (eps) Interfere with Rugose Polysaccharide Production in and Motility of Vibrio cholerae
A Ali, JA Johnson, AA Franco, DJ Metzger… - Infection and …, 2000 - Am Soc Microbiol
… the extracellular protein secretion system (gene designated eps) is … gene of the eps operon
abolished the production of rugose polysaccharide, reduced the secretion of cholera toxin …
abolished the production of rugose polysaccharide, reduced the secretion of cholera toxin …
Toxins and Type II Secretion Systems
ME Scott, M Sandkvist - Bacterial Protein Toxins, 2003 - Wiley Online Library
… toxin (CT) as the prototype to describe the type II secretion process. CT is the most intensely
studied protein of all factors that are secreted via … The vcpD and eps genes are specifically …
studied protein of all factors that are secreted via … The vcpD and eps genes are specifically …
Type II secretion and pathogenesis
M Sandkvist - Infection and immunity, 2001 - Am Soc Microbiol
… of additional type II secretion genes and the expansion of the type II secretion … type II
secretion genes homologous to the V. cholerae eps genes, they were unable to secrete the toxin B …
secretion genes homologous to the V. cholerae eps genes, they were unable to secrete the toxin B …
Genes required for extracellular secretion of enterotoxin are clustered in Vibrio cholerae
LJ Overbye, M Sandkvist, M Bagdasarian - Gene, 1993 - Elsevier
… Expression of eps genes under the control of bacteriophage … of toxin secretion by Vibrio
cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins …
cholerae investigated in strains harboring plasmids that encode heat-labile enterotoxins …
Interaction between the autokinase EpsE and EpsL in the cytoplasmic membrane is required for extracellular secretion in Vibrio cholerae.
M Sandkvist, M Bagdasarian, SP Howard… - The EMBO …, 1995 - embopress.org
… secretion of cholera toxin requires a large set of accessory proteins, which are encoded by
the eps genes and … gene is essential for extracellular secretion of toxin from Vcholerae. In the …
the eps genes and … gene is essential for extracellular secretion of toxin from Vcholerae. In the …