Genomic prediction of complex human traits: relatedness, trait architecture and predictive meta-models
A Spiliopoulou, R Nagy, ML Bermingham… - Human molecular …, 2015 - academic.oup.com
… genomic prediction of complex traits, it is not yet clear when dense or sparse models are
optimal. For genomic … when we examine genomic prediction of complex traits in humans, where …
optimal. For genomic … when we examine genomic prediction of complex traits in humans, where …
Multi-trait ensemble genomic prediction and simulations of recurrent selection highlight importance of complex trait genetic architecture for long-term genetic gains in …
… complex trait relationships … genomic prediction models that increase prediction accuracy
by exploiting pleiotropic effects among traits, and (iii) investigate how increased prediction …
by exploiting pleiotropic effects among traits, and (iii) investigate how increased prediction …
Genome-wide prediction of traits with different genetic architecture through efficient variable selection
… to learn about genetic trait architecture only if the trait has a … However, as soon as the trait
architecture becomes more … for GWA studies and genome-based prediction we tend to explore …
architecture becomes more … for GWA studies and genome-based prediction we tend to explore …
[HTML][HTML] A guide on deep learning for complex trait genomic prediction
M Pérez-Enciso, LM Zingaretti - Genes, 2019 - mdpi.com
… applications to genomic prediction, since … of genomic prediction theory and current limitations.
Second, we describe the theoretical concepts behind DL, including main DL architectures, …
Second, we describe the theoretical concepts behind DL, including main DL architectures, …
[HTML][HTML] Effect of genetic architecture on the prediction accuracy of quantitative traits in samples of unrelated individuals
… affecting complex traits, contributing to our knowledge of the biology of these traits. However…
, limiting our ability to predict quantitative trait phenotypes from high resolution genetic …
, limiting our ability to predict quantitative trait phenotypes from high resolution genetic …
[HTML][HTML] Comparison of whole-genome prediction models for traits with contrasting genetic architecture in a diversity panel of maize inbred lines
C Riedelsheimer, F Technow, AE Melchinger - BMC genomics, 2012 - Springer
… However, small gains in prediction accuracies can be achieved if the WGP model is … to the
genetic architecture of the trait. If the trait architecture is unknown eg for novel traits which only …
genetic architecture of the trait. If the trait architecture is unknown eg for novel traits which only …
Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture
ME Goddard, KE Kemper… - … of the Royal …, 2016 - royalsocietypublishing.org
… genomic prediction, mapping of causal variants and inference on the genetic architecture of
complex traits… the statistical model and its use for prediction of phenotype. This is followed by …
complex traits… the statistical model and its use for prediction of phenotype. This is followed by …
Multi-environment genomic prediction of plant traits using deep learners with dense architecture
A Montesinos-López… - … : Genes, Genomes …, 2018 - academic.oup.com
… genomic prediction is lacking. This paper evaluates prediction accuracy in the context of
genomic … (DL) methods with a densely connected network architecture, which is a type of ML …
genomic … (DL) methods with a densely connected network architecture, which is a type of ML …
[HTML][HTML] Accounting for trait architecture in genomic predictions of US Holstein cattle using a weighted realized relationship matrix
F Tiezzi, C Maltecca - Genetics Selection Evolution, 2015 - Springer
… Genome-wide association analyses were used to derive marker weights for creating weighted
genomic … exploit the genetic architecture of traits and produce more stable predictions. …
genomic … exploit the genetic architecture of traits and produce more stable predictions. …
[HTML][HTML] … architecture of complex traits and accuracy of genomic prediction: coat colour, milk-fat percentage, and type in Holstein cattle as contrasting model traits
… We also show that the accuracy of predicting genetic values is higher for traits with a … of
genomic prediction which can be achieved for this trait with the accuracy of genomic predictions …
genomic prediction which can be achieved for this trait with the accuracy of genomic predictions …
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