Accounting for Genetic Architecture Improves Sequence Based Genomic Prediction for a Drosophila Fitness Trait

U Ober, W Huang, M Magwire, M Schlather… - PLoS …, 2015 - journals.plos.org
… the genomic best linear unbiased prediction model is markedly improved when we combine
quantitative trait locus mapping with genomic prediction by … This trait-associated prediction

Expanding the BLUP alphabet for genomic prediction adaptable to the genetic architectures of complex traits

J Wang, Z Zhou, Z Zhang, H Li, D Liu, Q Zhang… - Heredity, 2018 - nature.com
… In contrast, genomic best linear unbiased prediction (gBLUP) … superior in prediction accuracy
for extremely complex traits. … technologies and traits with different genetic architectures. In …

Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds

L Fang, G Sahana, P Ma, G Su, Y Yu, S Zhang… - BMC genomics, 2017 - Springer
… ) may aid in the genomic prediction. Here, we hypothesized that the genomic variants of
complex traits might be enriched in a subset of genomic regions defined by genes grouped on …

The performance of phenomic selection depends on the genetic architecture of the target trait

X Zhu, HP Maurer, M Jenz, V Hahn… - Theoretical and Applied …, 2022 - Springer
prediction and genomic prediction for yield, yield-related traits and disease resistance traits,
… NIRS data from a single environment to predict trait performance at another environment, (3) …

Complex trait prediction from genome data: contrasting EBV in livestock to PRS in humans: genomic prediction

NR Wray, KE Kemper, BJ Hayes, ME Goddard… - Genetics, 2019 - academic.oup.com
… Next, we consider accuracy of out-of-sample prediction of PRS for which we find the theoretical
expectations of prediction accuracy under-recognized by practitioners. Last, we discuss …

Improving the accuracy of whole genome prediction for complex traits using the results of genome wide association studies

Z Zhang, U Ober, M Erbe, H Zhang, N Gao, J He, J Li… - PloS one, 2014 - journals.plos.org
… underlying genetic architecture via genome wide association … trait-specific genomic
relationship matrices which can exploit GWAS results in WGP via a best linear unbiased prediction (…

Genetic architecture and genomic predictive ability of apple quantitative traits across environments

M Jung, B Keller, M Roth, MJ Aranzana… - Horticulture …, 2022 - academic.oup.com
… genetic architecture and genomic predictive abilities for 30 quantitative traits across up to six
… recommendations for future implementation of genomic prediction tools in apple breeding. …

Genomic prediction using multi-trait weighted GBLUP accounting for heterogeneous variances and covariances across the genome

E Karaman, MS Lund, MT Anche… - G3: Genes, Genomes …, 2018 - academic.oup.com
trait GBLUP can yield accuracies of genomic prediction as high as Bayesian multi-trait genomic
prediction … The gain from a multi-trait weighted GBLUP analysis depends on factors, such …

Accuracy of whole-genome prediction using a genetic architecture-enhanced variance-covariance matrix

Z Zhang, M Erbe, J He, U Ober, N Gao… - … : Genes, Genomes …, 2015 - academic.oup.com
traits in animal, plant, and human populations is possible through whole-genome prediction
(WGP… Because the underlying genetic architecture of the trait of interest is an important factor …

Can deep learning improve genomic prediction of complex human traits?

P Bellot, G de Los Campos, M Pérez-Enciso - Genetics, 2018 - academic.oup.com
… So far, the application of NNs for genomic prediction of complex traits has … the prediction
of complex human traits using data from distantly related individuals. Achieving high prediction