Accounting for Genetic Architecture Improves Sequence Based Genomic Prediction for a Drosophila Fitness Trait
U Ober, W Huang, M Magwire, M Schlather… - PLoS …, 2015 - journals.plos.org
… the genomic best linear unbiased prediction model is markedly improved when we combine
quantitative trait locus mapping with genomic prediction by … This trait-associated prediction …
quantitative trait locus mapping with genomic prediction by … This trait-associated prediction …
Expanding the BLUP alphabet for genomic prediction adaptable to the genetic architectures of complex traits
… In contrast, genomic best linear unbiased prediction (gBLUP) … superior in prediction accuracy
for extremely complex traits. … technologies and traits with different genetic architectures. In …
for extremely complex traits. … technologies and traits with different genetic architectures. In …
Use of biological priors enhances understanding of genetic architecture and genomic prediction of complex traits within and between dairy cattle breeds
… ) may aid in the genomic prediction. Here, we hypothesized that the genomic variants of
complex traits might be enriched in a subset of genomic regions defined by genes grouped on …
complex traits might be enriched in a subset of genomic regions defined by genes grouped on …
The performance of phenomic selection depends on the genetic architecture of the target trait
X Zhu, HP Maurer, M Jenz, V Hahn… - Theoretical and Applied …, 2022 - Springer
… prediction and genomic prediction for yield, yield-related traits and disease resistance traits,
… NIRS data from a single environment to predict trait performance at another environment, (3) …
… NIRS data from a single environment to predict trait performance at another environment, (3) …
Complex trait prediction from genome data: contrasting EBV in livestock to PRS in humans: genomic prediction
… Next, we consider accuracy of out-of-sample prediction of PRS for which we find the theoretical
expectations of prediction accuracy under-recognized by practitioners. Last, we discuss …
expectations of prediction accuracy under-recognized by practitioners. Last, we discuss …
Improving the accuracy of whole genome prediction for complex traits using the results of genome wide association studies
Z Zhang, U Ober, M Erbe, H Zhang, N Gao, J He, J Li… - PloS one, 2014 - journals.plos.org
… underlying genetic architecture via genome wide association … trait-specific genomic
relationship matrices which can exploit GWAS results in WGP via a best linear unbiased prediction (…
relationship matrices which can exploit GWAS results in WGP via a best linear unbiased prediction (…
Genetic architecture and genomic predictive ability of apple quantitative traits across environments
M Jung, B Keller, M Roth, MJ Aranzana… - Horticulture …, 2022 - academic.oup.com
… genetic architecture and genomic predictive abilities for 30 quantitative traits across up to six
… recommendations for future implementation of genomic prediction tools in apple breeding. …
… recommendations for future implementation of genomic prediction tools in apple breeding. …
Genomic prediction using multi-trait weighted GBLUP accounting for heterogeneous variances and covariances across the genome
… trait GBLUP can yield accuracies of genomic prediction as high as Bayesian multi-trait genomic
prediction … The gain from a multi-trait weighted GBLUP analysis depends on factors, such …
prediction … The gain from a multi-trait weighted GBLUP analysis depends on factors, such …
Accuracy of whole-genome prediction using a genetic architecture-enhanced variance-covariance matrix
Z Zhang, M Erbe, J He, U Ober, N Gao… - … : Genes, Genomes …, 2015 - academic.oup.com
… traits in animal, plant, and human populations is possible through whole-genome prediction
(WGP… Because the underlying genetic architecture of the trait of interest is an important factor …
(WGP… Because the underlying genetic architecture of the trait of interest is an important factor …
Can deep learning improve genomic prediction of complex human traits?
… So far, the application of NNs for genomic prediction of complex traits has … the prediction
of complex human traits using data from distantly related individuals. Achieving high prediction …
of complex human traits using data from distantly related individuals. Achieving high prediction …