… Secondary prevention studies of transcatheter closure or medical therapy for patent foramen
ovale were required to include at least 10 patients followed for more than 1 year and to …

… PFO closure and 1,153 patients randomized to medical therapy. … the TC PFO closure group
when compared to medical treatment, … Transcatheter closure versus medical therapy of patent …

… PFO closure does not confer an advantage over medical therapy on the basis of this meta-analysis.
PFO closure should be recommended on a case to case basis as risks may outweigh …

… Case series reporting outcomes after transcatheter closure with at least 100 patients were
… transcatheter closure and medical therapy or case series reporting outcomes after medical …

… current literature favors transcatheter closure of a PFO over standard medical treatment for
… safety of transcatheter closure of PFO using the APFOO versus dual antiplatelet therapy with …

… transcatheter closure of PFO versus medical therapy after cryptogenic stroke suggests that
PFO closure … neurological events as compared with medical treatment alone. This difference …

… for all published RCTs comparing transcatheter PFO closure with medical therapy. We
used the items “PFO or patent foramen ovale,” “paradoxical embolism,” “PFO closure,” and “stroke …

… Randomized clinical trials are currently underway comparing medical therapy versus
device closure of PFO in patients with cryptogenic stroke, and until these results are available …

… We searched all the databases for randomized controlled trials comparing medical therapy
versus transcatheter closure of PFO for secondary prevention of cryptogenic stroke/TIA. In …

… comparison of medical therapy and transcatheter closure in 280 … therapy, 5.6% of patients
on oral anticoagulation therapy, and 0.6% of patients who underwent transcatheter closure …