Mechanisms of the antiinflammatory effects of αMSH: role of transcription factor NF‐κB and adhesion molecule expression

DH Kalden, T Scholzen, T Brzoska… - Annals of the New York …, 1999 - Wiley Online Library
… of α-MSH in the activation of the transcription factor NF-αB was also investigated. α-MSH
significantly … These findings indicate that modulation of the transcription factor NF-κB is a crucial …

The Role of αMSH as a Modulator of Cutaneous Inflammation

TA Luger, T Brzoska, TE Scholzen… - Annals of the New …, 2000 - Wiley Online Library
… -induced activation of transcription factors such as NFκB is downregulated by α-MSH. In a
… The activation of the transcription factor NFκB appears to be a crucial event in immune and …

α-Melanocyte-stimulating hormone inhibits the nuclear transcription factor NF-κB activation induced by various inflammatory agents

SK Manna, BB Aggarwal - The Journal of Immunology, 1998 - journals.aai.org
… of α-MSH on the activation of this transcription factor by a wide variety of inflammatory stimuli.
Electrophoretic mobility shift assay showed that α-MSH … of the transcription factor activating …

New insights into the functions of αMSH and related peptides in the immune system

TA Luger, TE Scholzen, T Brzoska… - Annals of the New York …, 2003 - Wiley Online Library
… At the molecular level, these effects of α-MSH are mediated via the inhibition of the … of
transcription factors such as NFκB. Not only α-MSH but also its C-terminal tripeptide (α-MSH 11–13…

Molecular basis of the αMSH/IL‐1 antagonism

T Brzoska, DH KALDEN, T Scholzen… - Annals of the New …, 1999 - Wiley Online Library
… of α-MSH on the IL-1β-induced activation of the nuclear factor κB (NFκB)-a major transcription
factor … Hence, the effect of α-MSH on IL-1β-induced transcription factor activation, and the …

Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors

P Wan, Y Hu, L He - Molecular and cellular biochemistry, 2011 - Springer
transcription factors and to reconstruct the regulatory network in modulating MITF [4–8]. In
this article, we summarize the transcription factors … response to ASP or MSH and is apparently …

Thyroid transcription factor‐1 regulates feeding behavior via melanocortin pathway in the hypothalamus

JG Kim, BS Park, CH Yun, HJ Kim, SS Kang… - Diabetes, 2011 - Am Diabetes Assoc
… thyroid transcription factor-1 (TTF-1) controls feeding behavior in the hypothalamus. This
study aims to identify the function of TTF-1 in the transcriptional regulation of AgRP and α-MSH

NF-κB transcription factor subunits in rat brain: colocalization of p65 and α-MSH

SA Joseph, C Tassorelli, AV Prasad, E Lynd-Balta - Peptides, 1996 - Elsevier
transcription factor in the rat brain, These studies were prompted by our previous demonstration
that this transcription factor … esis that the NF-KB transcription complex is involved in neuro…

[HTML][HTML] αMSH inhibits adipose inflammation via reducing FoxOs transcription and blocking Akt/JNK pathway in mice

G Liu, M Li, M Saeed, Y Xu, Q Ren, C Sun - Oncotarget, 2017 - ncbi.nlm.nih.gov
… The fusion protein TAT-HSA-α-MSH inhibits NF-κB activation in human and TNFα … Moreover,
we found that Foxo4 was a novel transcriptional factor of MC5R in aggravating adipose …

α-MSH and Foxc2 promote fatty acid oxidation through C/EBPβ negative transcription in mice adipose tissue

L Gan, Z Liu, Y Chen, D Luo, F Feng, G Liu, C Sun - Scientific Reports, 2016 - nature.com
α-MSH stimulates fatty acid oxidation in adipose tissue remains unclear, even though α-MSH
of the forkhead/winged helix transcription factor family in various organs and tissues, such …